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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ketendo</journal-id><journal-title-group><journal-title xml:lang="ru">Клиническая и экспериментальная тиреоидология</journal-title><trans-title-group xml:lang="en"><trans-title>Clinical and experimental thyroidology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1995-5472</issn><issn pub-type="epub">2310-3787</issn><publisher><publisher-name>Endocrinology Research Centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/ket10002</article-id><article-id custom-type="elpub" pub-id-type="custom">ketendo-10002</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>De Gustibus</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>De Gustibus</subject></subj-group></article-categories><title-group><article-title>Через годы, через расстояния…</article-title><trans-title-group xml:lang="en"><trans-title>Through years, across distances…</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6299-7219</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Герасимов</surname><given-names>Григорий Анатольевич</given-names></name><name name-style="western" xml:lang="en"><surname>Gerasimov</surname><given-names>Gregory A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук, профессор</p><p> </p></bio><bio xml:lang="en"><p>MD, PhD, Professor</p><p> </p></bio><email xlink:type="simple">gerasimovg@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>&lt;p&gt;Глобальная сеть по йоду&lt;/p&gt;</institution><country>Соединённые Штаты Америки</country></aff><aff xml:lang="en"><institution>&lt;p&gt;Iodine Global Network (IGN)&lt;/p&gt;</institution><country>United States</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>27</day><month>12</month><year>2018</year></pub-date><volume>14</volume><issue>3</issue><fpage>122</fpage><lpage>127</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Герасимов Г.А., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Герасимов Г.А.</copyright-holder><copyright-holder xml:lang="en">Gerasimov G.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.cet-endojournals.ru/jour/article/view/10002">https://www.cet-endojournals.ru/jour/article/view/10002</self-uri><abstract><p>Медицина – наука древняя. В современном понимании врачебная профессия стала формироваться после того, как кровопускание в качестве универсального способа восстановления баланса телесных соков в организме было заменено более научными и менее калечащими методами. Но в медицинской практике случается так, что новые методы диагностики и лечения уживаются с весьма древними, а некоторые традиционные подходы, ранее не имевшие надежного обоснования, получают солидную научную поддержку. Этот исторический процесс напоминает течение воды в реке: быстрое в стремнине, медленное вдоль берегов и малоподвижное в тихих заводях, на дне которых можно найти принесенные паводками ветхие отбросы и разнообразный мусор. Все это находится в кругообороте – что-то исчезает в пучине, а что-то неожиданно всплывает на поверхность. Скандал с отзывом из аптечной сети в США препарата из измельченной и высушенной щитовидной железы свиней напомнил о том, что в клинической практике могут мирно уживаться средства, известные со времен древней китайской медицины, и препараты, появившиеся относительно недавно благодаря современной фармацевтике. Правда, при одной существенной оговорке: качество таких препаратов должно контролироваться столь же тщательно, что и новейших средств. Современные технологии позволили анализировать геном обитателей наших внутренних органов, составляющих микробиоту, что позволило реабилитировать ранее считавшееся антинаучным представление о дисбактериозе (дисбиозе). Например, кишечные бактерии способны конкурировать с организмом “хозяина” за селен и даже усугублять его дефицит, а также модулировать биодоступность йодтиронинов. Не исключено, что кишечный дисбиоз может быть одной из причин мальабсорбции тироксина. Обо всем этом и многом другом в очередной авторской колонке “De Gustibus”.</p></abstract><trans-abstract xml:lang="en"><p>Medicine is an ancient science. In the modern sense, the medical profession began to form after bloodletting as a universal way of restoring the balance of bodily juices was replaced by more scientific and less crippling methods. But in medical practice it often happens that new methods of diagnosis and treatment get along with very ancient ones, and some traditional approaches, that previously had no reliable justification, receive solid scientific support. This historic process closely resembles the flow of water in a river: fast in the rapids, slow along the shores and sedentary in quiet creeks, at the bottom of which one can find shabby garbage brought by floods. All this is in a circuit – something disappears in the abyss, and something suddenly floats to the surface. The scandal in the USA with the recall of a medicine made from desiccated and dried porcine thyroid gland reminded us that some concoctions, which have been known since the times of ancient Chinese medicine, and drugs that appeared relatively recently thanks to modern pharmacology can easily coexist in clinical practice. With one essential caveat: the quality of such concoctions should be controlled as carefully as the newest drugs. Modern technologies have allowed us to analyze the genome of the inhabitants of our internal organs, that constitute the human microbiome. This made it possible to rehabilitate the concept of dysbacteriosis (dysbiosis), which was previously considered anti-scientific. For example, intestinal bacteria are able to compete with the host organism for selenium and even capable of aggravating its deficiency, as well as modulating the bioavailability of iodothyronines. It is possible that intestinal dysbiosis may be one of the causes of thyroxine malabsorption. All these and much more in this column “De Gustibus”.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>щитовидная железа</kwd><kwd>тироксин</kwd><kwd>сауна</kwd><kwd>микробиом</kwd><kwd>дисбиоз</kwd><kwd>селен</kwd><kwd>фагоциты</kwd></kwd-group><kwd-group xml:lang="en"><kwd>thyroid gland</kwd><kwd>thyroxin</kwd><kwd>sauna</kwd><kwd>microbiome</kwd><kwd>dysbiosis</kwd><kwd>selenium</kwd><kwd>phagocytes</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Medscape.com [Internet]. Brooks M. Thyroid tablets recalled in US because of impurity risk [cited 2018 Dec 30]. Available from: https://www.medscape.com/viewarticle/900606.</mixed-citation><mixed-citation xml:lang="en">Medscape.com [Internet]. Brooks M. Thyroid tablets recalled in US because of impurity risk [cited 2018 Dec 30]. 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