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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ketendo</journal-id><journal-title-group><journal-title xml:lang="ru">Клиническая и экспериментальная тиреоидология</journal-title><trans-title-group xml:lang="en"><trans-title>Clinical and experimental thyroidology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1995-5472</issn><issn pub-type="epub">2310-3787</issn><publisher><publisher-name>Endocrinology Research Centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/ket12702</article-id><article-id custom-type="elpub" pub-id-type="custom">ketendo-12707</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW</subject></subj-group></article-categories><title-group><article-title>Проект клинических рекомендаций по гипотиреозу</article-title><trans-title-group xml:lang="en"><trans-title>Draft of the clinical recommendations for diagnosis and treatment of hypothyroidism</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3026-6315</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фадеев</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Fadeev</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Фадеев Валентин Викторович, д.м.н., член-корр. РАН, профессор, кафедра эндокринологии №1 Института клинической медицины им. Н.В. Склифосовского, 119991, Москва, ул. Трубецкая, д. 8, стр. 2, eLibrary SPIN: 6825-8417</p></bio><bio xml:lang="en"><p>Valentin V. Fadeev, MD, PhD, Professor, 8-2 Trubetskaya str., Moscow 119991, Russia, eLibrary SPIN: 6825-8417</p></bio><email xlink:type="simple">walfad@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1500-1586</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Моргунова</surname><given-names>Т. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Morgunova</surname><given-names>T. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Моргунова Татьяна Борисовна, к.м.н., eLibrary SPIN: 3705-8599, Москва</p></bio><bio xml:lang="en"><p>Tatyana B. Morgunova, MD, PhD, eLibrary SPIN: 3705-8599, Moscow</p></bio><email xlink:type="simple">tanmorgun@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5634-7877</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мельниченко</surname><given-names>Г. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Melnichenko</surname><given-names>G. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мельниченко Галина Афанасьевна, д.м.н., профессор, академик РАН, eLibrary SPIN: 8615-0038, Москва</p></bio><bio xml:lang="en"><p>Galina A. Melnichenko, MD, PhD, Professor, eLibrary SPIN: 8615-0038, Moscow</p></bio><email xlink:type="simple">teofrast2000@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8175-7886</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дедов</surname><given-names>И. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Dedov</surname><given-names>I. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Дедов Иван Иванович, д.м.н., профессор, академик РАН, Researcher ID: D-3729-2014; Scopus Author ID: 7101843976;eLibrary SPIN: 5873-2280, Москва</p></bio><bio xml:lang="en"><p>Ivan I. Dedov, MD, PhD, Professor, Researcher ID: D-3729-2014, Scopus Author ID: 7101843976, eLibrary SPIN: 5873-2280, Moscow</p></bio><email xlink:type="simple">dedov@endocrincentr.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Первый Московский государственный медицинский университет им. И.М. Сеченова (Сеченовский университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I.M. Sechenov First Moscow State Medical University (Sechenov University)</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Национальный медицинский исследовательский центр эндокринологии</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Endocrinology Research Centre</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>15</day><month>08</month><year>2021</year></pub-date><volume>17</volume><issue>1</issue><fpage>4</fpage><lpage>13</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Фадеев В.В., Моргунова Т.Б., Мельниченко Г.А., Дедов И.И., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Фадеев В.В., Моргунова Т.Б., Мельниченко Г.А., Дедов И.И.</copyright-holder><copyright-holder xml:lang="en">Fadeev V.V., Morgunova T.B., Melnichenko G.A., Dedov I.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.cet-endojournals.ru/jour/article/view/12707">https://www.cet-endojournals.ru/jour/article/view/12707</self-uri><abstract><p>Гипотиреоз — одно из наиболее распространенных эндокринных заболеваний. Более 99% всех случаев гипотиреоза у взрослых приходится на первичный гипотиреоз. Наиболее часто гипотиреоз развивается вследствие хронического аутоиммунного тиреоидита, а также после медицинских манипуляций (ятрогенный гипотиреоз) — послеоперационный или в исходе терапии радиоактивным йодом. В статье представлен проект клинических рекомендаций по диагностике, лечению гипотиреоза в разных группах пациентов, включая беременных женщин.</p></abstract><trans-abstract xml:lang="en"><p>Hypothyroidism is one of the most common endocrine diseases. More than 99% of all cases of hypothyroidism in adults are due to primary hypothyroidism. Most often, hypothyroidism develops because of chronic autoimmune thyroiditis, as well as after medical manipulations (iatrogenic hypothyroidism) — postoperative or as a result of therapy with radioactive iodine. The article presents a draft of clinical guidelines for the diagnosis and treatment of hypothyroidism in different groups of patients, including pregnant women.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>гипотиреоз</kwd><kwd>диагностика</kwd><kwd>заместительная терапия</kwd><kwd>левотироксин</kwd></kwd-group><kwd-group xml:lang="en"><kwd>hypothyroidism</kwd><kwd>diagnosis</kwd><kwd>replacement therapy</kwd><kwd>levothyroxine</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Национальное руководство. Эндокринология / Под редакцией И.И. Дедова, Г.А. Мельниченко. — М.: «Геотар-Медиа»; 2016. — С. 604-616, 635-645.</mixed-citation><mixed-citation xml:lang="en">Nacional’noe rukovodstvo. Jendokrinologija. Ed. Dedov II, Melnichenko GA. Moscow: «Geotar-Media»; 2016: 604-616, 635-645. 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