ketendoКлиническая и экспериментальная тиреоидологияClinical and experimental thyroidology1995-54722310-3787Endocrinology Research Centre10.14341/ket12746ketendo-12746Research ArticleОбзоры литературыReview of literatureЙод-ограниченная диета перед терапией радиоактивным йодом - назначать или не назначатьLow-iodine diet before radioactive iodine therapy - to prescribe or not to prescribehttps://orcid.org/0000-0002-1891-9205ГусельниковаА. Р.GuselnikovaA. R.

Гусельникова Анастасия Романовна

117036, Москва, ул. Дм. Ульянова, д. 11

Anastasia R. Guselnikova

11 Dm. Ulyanova street, 117292, Moscow

hgdfh7@mail.ruhttps://orcid.org/0000-0002-6954-1126КорчагинаМ. О.KorchaginaM. O.

Корчагина Мария Олеговна, аспирант

117036, Москва, ул. Дм. Ульянова, д. 11

Maria O. Korchagina, postgraduate student

11 Dm. Ulyanova street, 117292, Moscow

kmylavender@gmail.comhttps://orcid.org/0000-0003-3785-0335ШереметаМ. С.SheremetaM. S.

Шеремета Марина Сергеевна, к.м.н.

117036, Москва, ул. Дм. Ульянова, д. 11

Marina S. Sheremeta, PhD

11 Dm. Ulyanova street, 117292, Moscow

marina888@yandex.ruНациональный медицинский исследовательский центр эндокринологииРоссияEndocrinology Research CentreRussian Federation2022120420231832935Copyright © Гусельникова А.Р., Корчагина М.О., Шеремета М.С., 20232023Гусельникова А.Р., Корчагина М.О., Шеремета М.С.Guselnikova A.R., Korchagina M.O., Sheremeta M.S.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.cet-endojournals.ru/jour/article/view/12746

Йод – важнейший микроэлемент в организме человека. Его основная функция – участие в синтезе гормонов щитовидной железы, тироксина (Т4) и трийодтиронина (Т3). Главный источник йода для организма человека – богатая этим микроэлементом пища. Содержание йода в продуктах питания сильно варьирует. В высокой концентрации йод содержится в морепродуктах, йодированной соли, а также молочных продуктах, яичных желтках. Кроме того, йод содержится в ряде лекарственных препаратов для наружного и внутреннего применения, биологически активных добавках, а также в йод-содержащих контрастных веществах.Диета с низким содержанием йода (менее 50 мкг в сутки) назначается перед проведением терапии радиоактивным йодом (РЙТ) по поводу заболеваний щитовидной железы, а именно тиреотоксикоза и дифференцированного рака щитовидной железы. В настоящее время не существует единого мнения относительно клинической пользы такой диеты, особенно в странах с низким потреблением йода, таких как Россия.Цель настоящего обзора – оценить необходимость и оптимальную продолжительность йод-ограниченной диеты, а также определить клинические характеристики, влияющие на результат РЙТ, основываясь на данных последних исследований.

Iodine is the most important trace element in the human body. Its main function is to participate in the synthesis of thyroid hormones, thyroxine (T4) and triiodothyronine (T3). The main source of iodine for humans is food rich in this trace element. The iodine content in foods varies greatly. The main sources of iodine are seafood, iodized salt, seaweed, as well as dairy products and egg yolks. In addition, iodine is found in a number of drugs for external and internal use, dietary supplements, and in iodinated contrast agents.Low-iodine diet (less than 50 μg per day) is prescribed before radioactive iodine therapy (RAIT) for thyroid diseases, namely hyperthyroidism and differentiated thyroid cancer. Currently, there is no consensus on the clinical benefits of such a diet, especially in countries with iodine deficiency, such as Russia.The aim of this review is to assess the need for a low-iodine diet and its optimal duration, as well as to determine the clinical characteristics affecting the outcome of RAIT, based on data from recent studies.

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The authors declare that there are no conflicts of interest present.