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<article article-type="review-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ketendo</journal-id><journal-title-group><journal-title xml:lang="ru">Клиническая и экспериментальная тиреоидология</journal-title><trans-title-group xml:lang="en"><trans-title>Clinical and experimental thyroidology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1995-5472</issn><issn pub-type="epub">2310-3787</issn><publisher><publisher-name>Endocrinology Research Centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/ket12776</article-id><article-id custom-type="elpub" pub-id-type="custom">ketendo-12776</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Обзоры</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Reviews</subject></subj-group></article-categories><title-group><article-title>Табакокурение, электронные сигареты и щитовидная железа: риски развития тиреоидной патологии</article-title><trans-title-group xml:lang="en"><trans-title>Tobacco smoking, e-cigarette and thyroid: what are the risks of thyroid disorders</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9954-7641</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Беловалова</surname><given-names>И. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Belovalova</surname><given-names>I. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Беловалова Ирина Михайловна, к.м.н.</p><p>Москва</p></bio><bio xml:lang="en"><p>Irina M. Belovalova, MD, PhD</p><p>Moscow</p></bio><email xlink:type="simple">belovalova.irina@endocrincentr.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2396-2766</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шугурова</surname><given-names>Е. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Shugurova</surname><given-names>E. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шугурова Екатерина Станиславовна, эндокринолог</p><p>Москва</p></bio><bio xml:lang="en"><p>Ekaterina S. Shugurova, MD</p><p>Moscow</p></bio><email xlink:type="simple">Shugurova.Ek@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6954-1126</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Корчагина</surname><given-names>М. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Korchagina</surname><given-names>M. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Корчагина Мария Олеговна, акушер-гинеколог </p><p>117036, Москва, ул. Дм. Ульянова, д. 11 </p></bio><bio xml:lang="en"><p>Maria O. Korchagina, MD</p><p>11 Dm. Ulyanova street, 117036 Moscow</p><p>   </p></bio><email xlink:type="simple">kmylavender@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0007-8620-2437</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Борхоева</surname><given-names>Т. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Borkhoeva</surname><given-names>T. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Борхоева Туяна Николаевна, эндокринолог</p><p>Москва</p></bio><bio xml:lang="en"><p>Tuyana N. Borkhoeva, MD</p><p>Moscow</p></bio><email xlink:type="simple">2yaana0309@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3785-0335</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шеремета</surname><given-names>М. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Sheremeta</surname><given-names>M. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шеремета Марина Сергеевна, к.м.н.</p><p>Москва</p></bio><bio xml:lang="en"><p>Marina S. Sheremeta, MD, PhD</p><p>Moscow</p></bio><email xlink:type="simple">marina888@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Национальный медицинский исследовательский центр эндокринологии<country>Россия</country></aff><aff xml:lang="en">Endocrinology Research Centre<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>27</day><month>02</month><year>2024</year></pub-date><volume>19</volume><issue>2</issue><fpage>11</fpage><lpage>17</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Беловалова И.М., Шугурова Е.С., Корчагина М.О., Борхоева Т.Н., Шеремета М.С., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Беловалова И.М., Шугурова Е.С., Корчагина М.О., Борхоева Т.Н., Шеремета М.С.</copyright-holder><copyright-holder xml:lang="en">Belovalova I.M., Shugurova E.S., Korchagina M.O., Borkhoeva T.N., Sheremeta M.S.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.cet-endojournals.ru/jour/article/view/12776">https://www.cet-endojournals.ru/jour/article/view/12776</self-uri><abstract><p>Табакокурение — глобальная проблема здравоохранения уже многие годы. Особенно она усугубилась с момента массового производства табачных изделий. Давно не секрет, что табакокурение провоцирует различные заболевания, в том числе эндокринные, и способствует их прогрессированию. В настоящее время известно о роли генетической предрасположенности к развитию тиреоидной патологии и потенциальной роли различных средовых факторов в манифестации заболеваний щитовидной железы (ЩЖ). Наряду с потреблением йода, табакокурение — существенный фактор риска, влияющий на функциональное состояние и объем ЩЖ. С появлением электронных сигарет как альтернативы табачным изделиям возник закономерный вопрос: какое воздействие они оказывают на тиреоидный статус?</p><p>Настоящий литературный обзор обобщает современные представления о влиянии курения на ЩЖ, включая его взаимосвязь с изменением функции ЩЖ, развитием и прогрессированием заболеваний ЩЖ.</p></abstract><trans-abstract xml:lang="en"><p>Tobacco smoking has been a global health problem for many years. It has especially worsened since the mass production of tobacco products. Tobacco smoking provokes various diseases, including endocrine diseases, and contributes to their progression. It is now known about the role of genetic predisposition to the development of thyroid pathology and the potential role of various environmental factors in the manifestation of thyroid diseases. Along with iodine intake, tobacco smoking is a significant risk factor affecting the functional status and volume of the thyroid gland. The introduction of electronic cigarettes as an alternative to tobacco products has raised a legitimate question: what effect do they have on thyroid status? The current literature review highlights current knowledge on the effects of smoking on the thyroid, including its relationship to changes in thyroid function and the development and progression of thyroid disorders.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>никотин</kwd><kwd>тиоцинат</kwd><kwd>экстракт сигаретного дыма</kwd><kwd>табачная продукция</kwd><kwd>табакокурение</kwd><kwd>болезнь Грейвса</kwd><kwd>эндокринная офтальмопатия</kwd><kwd>аутоиммунный тиреоидит</kwd><kwd>диффузный нетоксический зоб</kwd><kwd>рак щитовидной железы</kwd><kwd>электронные системы доставки никотина</kwd></kwd-group><kwd-group xml:lang="en"><kwd>nicotine</kwd><kwd>thiocyanates</kwd><kwd>cigarette smoke extract</kwd><kwd>tobacco products</kwd><kwd>tobacco smoking</kwd><kwd>graves ophthalmopathy</kwd><kwd>graves disease</kwd><kwd>goiter</kwd><kwd>thyroid neoplasms</kwd><kwd>electronic nicotine delivery systems</kwd></kwd-group><funding-group xml:lang="ru"><funding-statement>Работа выполнена в рамках государственного задания № 123021000041-6.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Who.int [Internet]. WORLD HEALTH ORGANIZATION: Health topics/Tobacco Available from: https://www.who.int/health-topics/tobacco#tab=tab_1</mixed-citation><mixed-citation xml:lang="en">Who.int [Internet]. WORLD HEALTH ORGANIZATION: Health topics/Tobacco Available from: https://www.who.int/health-topics/tobacco#tab=tab_1</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">ПРОЕКТ Концепции осуществления государственной политики противодействия потреблению табака на 2017 - 2022 годы и дальнейшую перспективу. Доступно по: https://minzdrav.gov.ru/documents/9544. Ссылка активна на 29.01.24</mixed-citation><mixed-citation xml:lang="en">PROEKT Koncepcii osushhestvleniya gosudarstvennoj politiki protivodejstviya potrebleniyu tabaka na 2017 - 2022 gody` i dal`nejshuyu perspektivu (in Russ.)]. Доступно по: https://minzdrav.gov.ru/documents/9544. Ссылка активна на 29.01.24</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Mucha L, Stephenson J, Morandi N, et al. Meta-analysis of disease risk associated with smoking, by gender and intensity of smoking. Gend Med. 2006;3(4):279-291. doi:10.1016/s1550-8579(06)80216-0</mixed-citation><mixed-citation xml:lang="en">Mucha L, Stephenson J, Morandi N, et al. Meta-analysis of disease risk associated with smoking, by gender and intensity of smoking. Gend Med. 2006;3(4):279-291. doi:10.1016/s1550-8579(06)80216-0</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Global Cardiovascular Risk Consortium, Magnussen C, Ojeda FM, et al. Global Effect of Modifiable Risk Factors on Cardiovascular Disease and Mortality. N Engl J Med. 2023;389(14):1273-1285. doi:10.1056/NEJMoa2206916</mixed-citation><mixed-citation xml:lang="en">Global Cardiovascular Risk Consortium, Magnussen C, Ojeda FM, et al. Global Effect of Modifiable Risk Factors on Cardiovascular Disease and Mortality. N Engl J Med. 2023;389(14):1273-1285. doi:10.1056/NEJMoa2206916</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Pan B, Jin X, Jun L, et al. The relationship between smoking and stroke: A meta-analysis. Medicine (Baltimore). 2019;98(12):e14872. doi:10.1097/MD.0000000000014872</mixed-citation><mixed-citation xml:lang="en">Pan B, Jin X, Jun L, et al. The relationship between smoking and stroke: A meta-analysis. Medicine (Baltimore). 2019;98(12):e14872. doi:10.1097/MD.0000000000014872</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Adeloye D, Song P, Zhu Y, et al. Global, regional, and national prevalence of, and risk factors for, chronic obstructive pulmonary disease (COPD) in 2019: a systematic review and modelling analysis. Lancet Respir Med. 2022;10(5):447-458. doi:10.1016/S2213-2600(21)00511-7</mixed-citation><mixed-citation xml:lang="en">Adeloye D, Song P, Zhu Y, et al. Global, regional, and national prevalence of, and risk factors for, chronic obstructive pulmonary disease (COPD) in 2019: a systematic review and modelling analysis. Lancet Respir Med. 2022;10(5):447-458. doi:10.1016/S2213-2600(21)00511-7</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Gandini S, Botteri E, Iodice S, et al. Tobacco smoking and cancer: a meta-analysis. Int J Cancer. 2008;122(1):155-164. doi:10.1002/ijc.23033</mixed-citation><mixed-citation xml:lang="en">Gandini S, Botteri E, Iodice S, et al. Tobacco smoking and cancer: a meta-analysis. Int J Cancer. 2008;122(1):155-164. doi:10.1002/ijc.23033</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Carter BD, Abnet CC, Feskanich D, et al. Smoking and mortality--beyond established causes. N Engl J Med. 2015;372(7):631-640. doi:10.1056/NEJMsa1407211</mixed-citation><mixed-citation xml:lang="en">Carter BD, Abnet CC, Feskanich D, et al. Smoking and mortality--beyond established causes. N Engl J Med. 2015;372(7):631-640. doi:10.1056/NEJMsa1407211</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Chang JT, Anic GM, Rostron BL, et al. Cigarette Smoking Reduction and Health Risks: A Systematic Review and Meta-analysis. Nicotine Tob Res. 2021;23(4):635-642. doi:10.1093/ntr/ntaa156</mixed-citation><mixed-citation xml:lang="en">Chang JT, Anic GM, Rostron BL, et al. Cigarette Smoking Reduction and Health Risks: A Systematic Review and Meta-analysis. Nicotine Tob Res. 2021;23(4):635-642. doi:10.1093/ntr/ntaa156</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Paulis MG, Abbas MF, Abbas AH. Subchronic Effects of E-Cigarette and Conventional Tobacco Smoke Exposure on Pituitary and Thyroid Glands Functions: Comparative Experimental Study. Egypt J. Forensic Sci. Appli. Toxicol, Vol 15(2), December supp. 2015</mixed-citation><mixed-citation xml:lang="en">Paulis MG, Abbas MF, Abbas AH. Subchronic Effects of E-Cigarette and Conventional Tobacco Smoke Exposure on Pituitary and Thyroid Glands Functions: Comparative Experimental Study. Egypt J. Forensic Sci. Appli. Toxicol, Vol 15(2), December supp. 2015</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Kapoor D, Jones TH. Smoking and hormones in health and endocrine disorders. Eur J Endocrinol. 2005;152(4):491-499. doi:10.1530/eje.1.01867</mixed-citation><mixed-citation xml:lang="en">Kapoor D, Jones TH. Smoking and hormones in health and endocrine disorders. Eur J Endocrinol. 2005;152(4):491-499. doi:10.1530/eje.1.01867</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Babić Leko M, Gunjača I, Pleić N, Zemunik T. Environmental Factors Affecting Thyroid-Stimulating Hormone and Thyroid Hormone Levels. Int J Mol Sci. 2021;22(12):6521. Published 2021 Jun 17. doi:10.3390/ijms22126521</mixed-citation><mixed-citation xml:lang="en">Babić Leko M, Gunjača I, Pleić N, Zemunik T. Environmental Factors Affecting Thyroid-Stimulating Hormone and Thyroid Hormone Levels. Int J Mol Sci. 2021;22(12):6521. Published 2021 Jun 17. doi:10.3390/ijms22126521</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Kang J, Kong E, Choi J. Associations of Urinary Cotinine-Verified Active and Passive Smoking with Thyroid Function: Analysis of Population-Based Nationally Representative Data. Thyroid. 2018;28(5):583-592. doi:10.1089/thy.2017.0567</mixed-citation><mixed-citation xml:lang="en">Kang J, Kong E, Choi J. Associations of Urinary Cotinine-Verified Active and Passive Smoking with Thyroid Function: Analysis of Population-Based Nationally Representative Data. Thyroid. 2018;28(5):583-592. doi:10.1089/thy.2017.0567</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Asvold BO, Bjøro T, Nilsen TI, Vatten LJ. Tobacco smoking and thyroid function: a population-based study. Arch Intern Med. 2007;167(13):1428-1432. doi:10.1001/archinte.167.13.1428</mixed-citation><mixed-citation xml:lang="en">Asvold BO, Bjøro T, Nilsen TI, Vatten LJ. Tobacco smoking and thyroid function: a population-based study. Arch Intern Med. 2007;167(13):1428-1432. doi:10.1001/archinte.167.13.1428</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Utiger RD. Effects of smoking on thyroid function. Eur J Endocrinol. 1998;138(4):368-369. doi:10.1530/eje.0.1380368</mixed-citation><mixed-citation xml:lang="en">Utiger RD. Effects of smoking on thyroid function. Eur J Endocrinol. 1998;138(4):368-369. doi:10.1530/eje.0.1380368</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Sawicka-Gutaj N, Gutaj P, Sowiński J, et al. Influence of cigarette smoking on thyroid gland--an update. Endokrynol Pol. 2014;65(1):54-62. doi:10.5603/EP.2014.0008.</mixed-citation><mixed-citation xml:lang="en">Sawicka-Gutaj N, Gutaj P, Sowiński J, et al. Influence of cigarette smoking on thyroid gland--an update. Endokrynol Pol. 2014;65(1):54-62. doi:10.5603/EP.2014.0008.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Hegedüs L, Karstrup S, Veiergang D, et al. High frequency of goitre in cigarette smokers. Clin Endocrinol (Oxf). 1985;22(3):287-292. doi:10.1111/j.1365-2265.1985.tb03242.x</mixed-citation><mixed-citation xml:lang="en">Hegedüs L, Karstrup S, Veiergang D, et al. High frequency of goitre in cigarette smokers. Clin Endocrinol (Oxf). 1985;22(3):287-292. doi:10.1111/j.1365-2265.1985.tb03242.x</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Petersen K, Lindstedt G, Lundberg PA, et al. Thyroid disease in middle-aged and elderly Swedish women: thyroid-related hormones, thyroid dysfunction and goitre in relation to age and smoking. J Intern Med. 1991;229(5):407-413. doi:10.1111/j.1365-2796.1991.tb00367.x</mixed-citation><mixed-citation xml:lang="en">Petersen K, Lindstedt G, Lundberg PA, et al. Thyroid disease in middle-aged and elderly Swedish women: thyroid-related hormones, thyroid dysfunction and goitre in relation to age and smoking. J Intern Med. 1991;229(5):407-413. doi:10.1111/j.1365-2796.1991.tb00367.x</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Kim J, Song H, Lee J, et al. Smoking and passive smoking increases mortality through mediation effect of cadmium exposure in the United States. Sci Rep. 2023 Mar 8;13(1):3878. doi: 10.1038/s41598-023-30988-z.</mixed-citation><mixed-citation xml:lang="en">Kim J, Song H, Lee J, et al. Smoking and passive smoking increases mortality through mediation effect of cadmium exposure in the United States. Sci Rep. 2023 Mar 8;13(1):3878. doi: 10.1038/s41598-023-30988-z.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Picciotto MR, Kenny PJ. Mechanisms of Nicotine Addiction. Cold Spring Harb Perspect Med. 2021;11(5):a039610. doi:10.1101/cshperspect.a039610</mixed-citation><mixed-citation xml:lang="en">Picciotto MR, Kenny PJ. Mechanisms of Nicotine Addiction. Cold Spring Harb Perspect Med. 2021;11(5):a039610. doi:10.1101/cshperspect.a039610</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Tweed JO, Hsia SH, Lutfy K, Friedman TC. The endocrine effects of nicotine and cigarette smoke. Trends Endocrinol Metab. 2012;23(7):334-342. doi:10.1016/j.tem.2012.03.006</mixed-citation><mixed-citation xml:lang="en">Tweed JO, Hsia SH, Lutfy K, Friedman TC. The endocrine effects of nicotine and cigarette smoke. Trends Endocrinol Metab. 2012;23(7):334-342. doi:10.1016/j.tem.2012.03.006</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Vestergaard P. Smoking and thyroid disorders--a meta-analysis. Eur J Endocrinol. 2002;146(2):153-161. doi:10.1530/eje.0.1460153</mixed-citation><mixed-citation xml:lang="en">Vestergaard P. Smoking and thyroid disorders--a meta-analysis. Eur J Endocrinol. 2002;146(2):153-161. doi:10.1530/eje.0.1460153</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Colzani R, Fang SL, Alex S, et al. The effect of nicotine on thyroid function in rats. Metabolism. 1998;47(2):154-157. doi:10.1016/s0026-0495(98)90212-8</mixed-citation><mixed-citation xml:lang="en">Colzani R, Fang SL, Alex S, et al. The effect of nicotine on thyroid function in rats. Metabolism. 1998;47(2):154-157. doi:10.1016/s0026-0495(98)90212-8</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Alzoubi KH, Aleisa AM, Gerges NZ, et al. Nicotine reverses adult-onset hypothyroidism-induced impairment of learning and memory: Behavioral and electrophysiological studies. J Neurosci Res. 2006;84(5):944-953. doi:10.1002/jnr.21014</mixed-citation><mixed-citation xml:lang="en">Alzoubi KH, Aleisa AM, Gerges NZ, et al. Nicotine reverses adult-onset hypothyroidism-induced impairment of learning and memory: Behavioral and electrophysiological studies. J Neurosci Res. 2006;84(5):944-953. doi:10.1002/jnr.21014</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Rehan M, Zargar UR, Sheikh IA, et al. Potential Disruption of Systemic Hormone Transport by Tobacco Alkaloids Using Computational Approaches. Toxics. 2022;10(12):727. Published 2022 Nov 26. doi:10.3390/toxics10120727</mixed-citation><mixed-citation xml:lang="en">Rehan M, Zargar UR, Sheikh IA, et al. Potential Disruption of Systemic Hormone Transport by Tobacco Alkaloids Using Computational Approaches. Toxics. 2022;10(12):727. Published 2022 Nov 26. doi:10.3390/toxics10120727</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Fukayama H, Nasu M, Murakami S, Sugawara M. Examination of antithyroid effects of smoking products in cultured thyroid follicles: only thiocyanate is a potent antithyroid agent. Acta Endocrinol (Copenh). 1992;127(6):520-525. doi:10.1530/acta.0.1270520</mixed-citation><mixed-citation xml:lang="en">Fukayama H, Nasu M, Murakami S, Sugawara M. Examination of antithyroid effects of smoking products in cultured thyroid follicles: only thiocyanate is a potent antithyroid agent. Acta Endocrinol (Copenh). 1992;127(6):520-525. doi:10.1530/acta.0.1270520</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Serrano-Nascimento C, Nunes MT. Perchlorate, nitrate, and thiocyanate: Environmental relevant NIS-inhibitors pollutants and their impact on thyroid function and human health. Front Endocrinol (Lausanne). 2022;13:995503. Published 2022 Oct 21. doi:10.3389/fendo.2022.995503</mixed-citation><mixed-citation xml:lang="en">Serrano-Nascimento C, Nunes MT. Perchlorate, nitrate, and thiocyanate: Environmental relevant NIS-inhibitors pollutants and their impact on thyroid function and human health. Front Endocrinol (Lausanne). 2022;13:995503. Published 2022 Oct 21. doi:10.3389/fendo.2022.995503</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Tonacchera M, Pinchera A, Dimida A, et al. Relative potencies and additivity of perchlorate, thiocyanate, nitrate, and iodide on the inhibition of radioactive iodide uptake by the human sodium iodide symporter. Thyroid (2004) 14(12):1012–9. doi: 10.1089/thy.2004.14.1012</mixed-citation><mixed-citation xml:lang="en">Tonacchera M, Pinchera A, Dimida A, et al. Relative potencies and additivity of perchlorate, thiocyanate, nitrate, and iodide on the inhibition of radioactive iodide uptake by the human sodium iodide symporter. Thyroid (2004) 14(12):1012–9. doi: 10.1089/thy.2004.14.1012</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Hayashi M, Futawaka K, Matsushita M, et al. Cigarette Smoke Extract Disrupts Transcriptional Activities Mediated by Thyroid Hormones and Its Receptors. Biol Pharm Bull. 2018;41(3):383-393. doi: 10.1248/bpb.b17-00735.</mixed-citation><mixed-citation xml:lang="en">Hayashi M, Futawaka K, Matsushita M, et al. Cigarette Smoke Extract Disrupts Transcriptional Activities Mediated by Thyroid Hormones and Its Receptors. Biol Pharm Bull. 2018;41(3):383-393. doi: 10.1248/bpb.b17-00735.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Gruppen EG, Kootstra-Ros J, Kobold AM, et al. Cigarette smoking is associated with higher thyroid hormone and lower TSH levels: the PREVEND study. Endocrine. 2020 Mar;67(3):613-622. doi: 10.1007/s12020-019-02125-2.</mixed-citation><mixed-citation xml:lang="en">Gruppen EG, Kootstra-Ros J, Kobold AM, et al. Cigarette smoking is associated with higher thyroid hormone and lower TSH levels: the PREVEND study. Endocrine. 2020 Mar;67(3):613-622. doi: 10.1007/s12020-019-02125-2.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Jorde R, Sundsfjord J. Serum TSH levels in smokers and non-smokers. The 5th Tromsø study. Exp Clin Endocrinol Diabetes. 2006;114(7):343-347. doi:10.1055/s-2006-924264</mixed-citation><mixed-citation xml:lang="en">Jorde R, Sundsfjord J. Serum TSH levels in smokers and non-smokers. The 5th Tromsø study. Exp Clin Endocrinol Diabetes. 2006;114(7):343-347. doi:10.1055/s-2006-924264</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Bartalena L, Bogazzi F, Tanda ML, et al. Cigarette smoking and the thyroid. Eur J Endocrinol. 1995;133(5):507-512. doi:10.1530/eje.0.1330507</mixed-citation><mixed-citation xml:lang="en">Bartalena L, Bogazzi F, Tanda ML, et al. Cigarette smoking and the thyroid. Eur J Endocrinol. 1995;133(5):507-512. doi:10.1530/eje.0.1330507</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Fukayama H, Nasu M, Murakami S, et al. Examination of antithyroid effects of smoking products in cultured thyroid follicles: only thiocyanate is a potent antithyroid agent. Acta Endocrinol (Copenh). 1992;127(6):520-525. doi:10.1530/acta.0.1270520</mixed-citation><mixed-citation xml:lang="en">Fukayama H, Nasu M, Murakami S, et al. Examination of antithyroid effects of smoking products in cultured thyroid follicles: only thiocyanate is a potent antithyroid agent. Acta Endocrinol (Copenh). 1992;127(6):520-525. doi:10.1530/acta.0.1270520</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Prummel MF, Wiersinga WM. Smoking and risk of Graves' disease. JAMA 1993:269:479-82. doi:10.1001/jama.269.4.479</mixed-citation><mixed-citation xml:lang="en">Prummel MF, Wiersinga WM. Smoking and risk of Graves' disease. JAMA 1993:269:479-82. doi:10.1001/jama.269.4.479</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Ericsson UB, Lindgärde F. Effects of cigarette smoking on thyroid function and the prevalence of goitre, thyrotoxicosis and autoimmune thyroiditis. J Intern Med. 1991;229(1):67-71. doi:10.1111/j.1365-2796.1991.tb00308.x</mixed-citation><mixed-citation xml:lang="en">Ericsson UB, Lindgärde F. Effects of cigarette smoking on thyroid function and the prevalence of goitre, thyrotoxicosis and autoimmune thyroiditis. J Intern Med. 1991;229(1):67-71. doi:10.1111/j.1365-2796.1991.tb00308.x</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Wiersinga WM. Smoking and thyroid. Clin Endocrinol (Oxf). 2013 Aug;79(2):145-51. doi: 10.1111/cen.12222.</mixed-citation><mixed-citation xml:lang="en">Wiersinga WM. Smoking and thyroid. Clin Endocrinol (Oxf). 2013 Aug;79(2):145-51. doi: 10.1111/cen.12222.</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Antonelli A, Ferrari SM, Ragusa F, et al. Graves' disease: Epidemiology, genetic and environmental risk factors and viruses. Best Pract Res Clin Endocrinol Metab. 2020;34(1):101387. doi:10.1016/j.beem.2020.101387</mixed-citation><mixed-citation xml:lang="en">Antonelli A, Ferrari SM, Ragusa F, et al. Graves' disease: Epidemiology, genetic and environmental risk factors and viruses. Best Pract Res Clin Endocrinol Metab. 2020;34(1):101387. doi:10.1016/j.beem.2020.101387</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Kurzynska A, Przybylik-Mazurek E, Węgrzynowicz K, et al. Wpływ wybranych czynników biologicznych oraz środowiskowych na przebieg i wystąpienie powikłań u pacjentów z chorobą Gravesa-Basedowa [Influence of selected endogenous and environmental factors on the course and complications of Grave's disease]. Przegl Lek. 2014;71(12):672-6. Polish. PMID: 25951694.</mixed-citation><mixed-citation xml:lang="en">Kurzynska A, Przybylik-Mazurek E, Węgrzynowicz K, et al. Wpływ wybranych czynników biologicznych oraz środowiskowych na przebieg i wystąpienie powikłań u pacjentów z chorobą Gravesa-Basedowa [Influence of selected endogenous and environmental factors on the course and complications of Grave's disease]. Przegl Lek. 2014;71(12):672-6. Polish. PMID: 25951694.</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Shine B, Fells P, Edwards OM, et al. Association between Graves' ophthalmopathy and smoking. Lancet. 1990;335(8700):1261-1263. doi:10.1016/0140-6736(90)91315-2</mixed-citation><mixed-citation xml:lang="en">Shine B, Fells P, Edwards OM, et al. Association between Graves' ophthalmopathy and smoking. Lancet. 1990;335(8700):1261-1263. doi:10.1016/0140-6736(90)91315-2</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Träisk F, Tallstedt L, Abraham-Nordling M, et al. Thyroid-associated ophthalmopathy after treatment for Graves' hyperthyroidism with antithyroid drugs or iodine-131. J Clin Endocrinol Metab. 2009;94(10):3700-3707. doi:10.1210/jc.2009-0747</mixed-citation><mixed-citation xml:lang="en">Träisk F, Tallstedt L, Abraham-Nordling M, et al. Thyroid-associated ophthalmopathy after treatment for Graves' hyperthyroidism with antithyroid drugs or iodine-131. J Clin Endocrinol Metab. 2009;94(10):3700-3707. doi:10.1210/jc.2009-0747</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Bartalena L, Piantanida E. Cigarette smoking: number one enemy for Graves ophthalmopathy. Pol Arch Med Wewn. 2016;126(10):725-726. doi:10.20452/pamw.3592</mixed-citation><mixed-citation xml:lang="en">Bartalena L, Piantanida E. Cigarette smoking: number one enemy for Graves ophthalmopathy. Pol Arch Med Wewn. 2016;126(10):725-726. doi:10.20452/pamw.3592</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">Pfeilschifter J, Ziegler R. Smoking and endocrine ophthalmopathy: impact of smoking severity and current vs lifetime cigarette consumption. Clin Endocrinol (Oxf). 1996;45(4):477-481. doi:10.1046/j.1365-2265.1996.8220832.x</mixed-citation><mixed-citation xml:lang="en">Pfeilschifter J, Ziegler R. Smoking and endocrine ophthalmopathy: impact of smoking severity and current vs lifetime cigarette consumption. Clin Endocrinol (Oxf). 1996;45(4):477-481. doi:10.1046/j.1365-2265.1996.8220832.x</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Choi W, Li Y, Ji YS, et al. Oxidative stress markers in tears of patients with Graves' orbitopathy and their correlation with clinical activity score. BMC Ophthalmol. 2018;18(1):303. Published 2018 Nov 21. doi:10.1186/s12886-018-0969-x</mixed-citation><mixed-citation xml:lang="en">Choi W, Li Y, Ji YS, et al. Oxidative stress markers in tears of patients with Graves' orbitopathy and their correlation with clinical activity score. BMC Ophthalmol. 2018;18(1):303. Published 2018 Nov 21. doi:10.1186/s12886-018-0969-x</mixed-citation></citation-alternatives></ref><ref id="cit44"><label>44</label><citation-alternatives><mixed-citation xml:lang="ru">Cawood TJ, Moriarty P, O'Farrelly C, et al. Smoking and thyroid-associated ophthalmopathy: A novel explanation of the biological link. J Clin Endocrinol Metab. 2007 Jan;92(1):59-64. doi: 10.1210/jc.2006-1824.</mixed-citation><mixed-citation xml:lang="en">Cawood TJ, Moriarty P, O'Farrelly C, et al. Smoking and thyroid-associated ophthalmopathy: A novel explanation of the biological link. J Clin Endocrinol Metab. 2007 Jan;92(1):59-64. doi: 10.1210/jc.2006-1824.</mixed-citation></citation-alternatives></ref><ref id="cit45"><label>45</label><citation-alternatives><mixed-citation xml:lang="ru">Francus T, Manzo G, Canki M, et al. Two peaks of interleukin 1 expression in human leukocytes cultured with tobacco glycoprotein. J Exp Med. 1989;170(1):327-332. doi:10.1084/jem.170.1.327</mixed-citation><mixed-citation xml:lang="en">Francus T, Manzo G, Canki M, et al. Two peaks of interleukin 1 expression in human leukocytes cultured with tobacco glycoprotein. J Exp Med. 1989;170(1):327-332. doi:10.1084/jem.170.1.327</mixed-citation></citation-alternatives></ref><ref id="cit46"><label>46</label><citation-alternatives><mixed-citation xml:lang="ru">Hofbauer LC, Mühlberg T, König A, et al. Soluble interleukin-1 receptor antagonist serum levels in smokers and nonsmokers with Graves' ophthalmopathy undergoing orbital radiotherapy. J Clin Endocrinol Metab. 1997;82(7):2244-2247. doi:10.1210/jcem.82.7.4068</mixed-citation><mixed-citation xml:lang="en">Hofbauer LC, Mühlberg T, König A, et al. Soluble interleukin-1 receptor antagonist serum levels in smokers and nonsmokers with Graves' ophthalmopathy undergoing orbital radiotherapy. J Clin Endocrinol Metab. 1997;82(7):2244-2247. doi:10.1210/jcem.82.7.4068</mixed-citation></citation-alternatives></ref><ref id="cit47"><label>47</label><citation-alternatives><mixed-citation xml:lang="ru">Quadbeck B, Roggenbuck U, Janssen OE, et al. Impact of smoking on the course of Graves’ disease after withdrawal of antithyroid drugs. Exp Clin Endocrinol Diabetes. 2006; 114: 406–411. https://doi.org/10.1055/s-2006-924065</mixed-citation><mixed-citation xml:lang="en">Quadbeck B, Roggenbuck U, Janssen OE, et al. Impact of smoking on the course of Graves’ disease after withdrawal of antithyroid drugs. Exp Clin Endocrinol Diabetes. 2006; 114: 406–411. https://doi.org/10.1055/s-2006-924065</mixed-citation></citation-alternatives></ref><ref id="cit48"><label>48</label><citation-alternatives><mixed-citation xml:lang="ru">Plazinska MT, Sawicka-Gutaj N, Czarnywojtek A, et al. Radioiodine therapy and Graves' disease - Myths and reality. PLoS One. 2020;15(1):e0226495. Published 2020 Jan 13. doi:10.1371/journal.pone.0226495</mixed-citation><mixed-citation xml:lang="en">Plazinska MT, Sawicka-Gutaj N, Czarnywojtek A, et al. Radioiodine therapy and Graves' disease - Myths and reality. PLoS One. 2020;15(1):e0226495. Published 2020 Jan 13. doi:10.1371/journal.pone.0226495</mixed-citation></citation-alternatives></ref><ref id="cit49"><label>49</label><citation-alternatives><mixed-citation xml:lang="ru">Czarnywojtek A, Komar-Rychlicka K, Zgorzalewicz-Stachowiak M, et al. Efficacy and safety of radioiodine therapy for mild Graves ophthalmopathy depending on cigarette consumption: a 6 month follow up. Pol Arch Med Wewn. 2016;126(10):746-753. doi:10.20452/pamw.3505</mixed-citation><mixed-citation xml:lang="en">Czarnywojtek A, Komar-Rychlicka K, Zgorzalewicz-Stachowiak M, et al. Efficacy and safety of radioiodine therapy for mild Graves ophthalmopathy depending on cigarette consumption: a 6 month follow up. Pol Arch Med Wewn. 2016;126(10):746-753. doi:10.20452/pamw.3505</mixed-citation></citation-alternatives></ref><ref id="cit50"><label>50</label><citation-alternatives><mixed-citation xml:lang="ru">Caulley L, Johnson-Obaseki S, Luo L, et al. Risk factors for postoperative complications in total thyroidectomy: A retrospective, risk-adjusted analysis from the National Surgical Quality Improvement Program. Medicine (Baltimore). 2017 Feb;96(5):e5752. doi: 10.1097/MD.0000000000005752.</mixed-citation><mixed-citation xml:lang="en">Caulley L, Johnson-Obaseki S, Luo L, et al. Risk factors for postoperative complications in total thyroidectomy: A retrospective, risk-adjusted analysis from the National Surgical Quality Improvement Program. Medicine (Baltimore). 2017 Feb;96(5):e5752. doi: 10.1097/MD.0000000000005752.</mixed-citation></citation-alternatives></ref><ref id="cit51"><label>51</label><citation-alternatives><mixed-citation xml:lang="ru">Belin RM, Astor BC, Powe NR, et al. Smoke exposure is associated with a lower prevalence of serum thyroid autoantibodies and thyrotropin concentration elevation and a higher prevalence of mild thyrotropin concentration suppression in the third National Health and Nutrition Examination Survey (NHANES III). J Clin Endocrinol Metab. 2004;89(12):6077-6086. doi:10.1210/jc.2004-0431</mixed-citation><mixed-citation xml:lang="en">Belin RM, Astor BC, Powe NR, et al. Smoke exposure is associated with a lower prevalence of serum thyroid autoantibodies and thyrotropin concentration elevation and a higher prevalence of mild thyrotropin concentration suppression in the third National Health and Nutrition Examination Survey (NHANES III). J Clin Endocrinol Metab. 2004;89(12):6077-6086. doi:10.1210/jc.2004-0431</mixed-citation></citation-alternatives></ref><ref id="cit52"><label>52</label><citation-alternatives><mixed-citation xml:lang="ru">Kim SJ, Kim MJ, Yoon SG, et al. Impact of smoking on thyroid gland: dose-related effect of urinary cotinine levels on thyroid function and thyroid autoimmunity. Sci Rep. 2019;9(1):4213. Published 2019 Mar 12. doi:10.1038/s41598-019-40708-1</mixed-citation><mixed-citation xml:lang="en">Kim SJ, Kim MJ, Yoon SG, et al. Impact of smoking on thyroid gland: dose-related effect of urinary cotinine levels on thyroid function and thyroid autoimmunity. Sci Rep. 2019;9(1):4213. Published 2019 Mar 12. doi:10.1038/s41598-019-40708-1</mixed-citation></citation-alternatives></ref><ref id="cit53"><label>53</label><citation-alternatives><mixed-citation xml:lang="ru">Park S, Kim WG, Jeon MJ, et al. Serum thyroid-stimulating hormone levels and smoking status: Data from the Korean National Health and Nutrition Examination Survey VI. Clin Endocrinol (Oxf). 2018;88(6):969-976. doi:10.1111/cen.13606</mixed-citation><mixed-citation xml:lang="en">Park S, Kim WG, Jeon MJ, et al. Serum thyroid-stimulating hormone levels and smoking status: Data from the Korean National Health and Nutrition Examination Survey VI. Clin Endocrinol (Oxf). 2018;88(6):969-976. doi:10.1111/cen.13606</mixed-citation></citation-alternatives></ref><ref id="cit54"><label>54</label><citation-alternatives><mixed-citation xml:lang="ru">Knudsen N, Bülow I, Laurberg P, Ovesen L, Perrild H, Jørgensen T. Association of tobacco smoking with goiter in a low-iodine-intake area. Arch Intern Med. 2002;162(4):439-443. doi:10.1001/archinte.162.4.439</mixed-citation><mixed-citation xml:lang="en">Knudsen N, Bülow I, Laurberg P, Ovesen L, Perrild H, Jørgensen T. Association of tobacco smoking with goiter in a low-iodine-intake area. Arch Intern Med. 2002;162(4):439-443. doi:10.1001/archinte.162.4.439</mixed-citation></citation-alternatives></ref><ref id="cit55"><label>55</label><citation-alternatives><mixed-citation xml:lang="ru">Волкова А.Р., Красильникова Е.И., Беркович О.А. и др. Функциональное состояние щитовидной железы, курение и кардиоваскулярный риск у больных ишемической болезнью сердца. Ученые записки СПбГМУ им. акад. И.П. Павлова. 2010; 17 (2): 17–21.</mixed-citation><mixed-citation xml:lang="en">Volkova A.R., Krasilnikova E.I., Berkovich O.A. et al. Thyroid gland function, smoking, and cardiovascular risk in heart ischemic disease patients. The Scientific Notes of the Pavlov University. 2010; 17 (2): 17–21 (in Russ).]</mixed-citation></citation-alternatives></ref><ref id="cit56"><label>56</label><citation-alternatives><mixed-citation xml:lang="ru">Lee JH, Chai YJ, Yi KH. Effect of Cigarette Smoking on Thyroid Cancer: Meta-Analysis. Endocrinol Metab (Seoul). 2021. Jun;36(3):590-598. doi: 10.3803/EnM.2021.954.</mixed-citation><mixed-citation xml:lang="en">Lee JH, Chai YJ, Yi KH. Effect of Cigarette Smoking on Thyroid Cancer: Meta-Analysis. Endocrinol Metab (Seoul). 2021. Jun;36(3):590-598. doi: 10.3803/EnM.2021.954.</mixed-citation></citation-alternatives></ref><ref id="cit57"><label>57</label><citation-alternatives><mixed-citation xml:lang="ru">Zhang L, Fang C, Liu L, et al. A case-control study of urinary levels of iodine, perchlorate and thiocyanate and risk of papillary thyroid cancer. Environ Int. 2018;120:388-393. doi:10.1016/j.envint.2018.08.024</mixed-citation><mixed-citation xml:lang="en">Zhang L, Fang C, Liu L, et al. A case-control study of urinary levels of iodine, perchlorate and thiocyanate and risk of papillary thyroid cancer. Environ Int. 2018;120:388-393. doi:10.1016/j.envint.2018.08.024</mixed-citation></citation-alternatives></ref><ref id="cit58"><label>58</label><citation-alternatives><mixed-citation xml:lang="ru">Mack WJ, Preston-Martin S, Dal Maso L, et al. A pooled analysis of case-control studies of thyroid cancer: cigarette smoking and consumption of alcohol, coffee, and tea. Cancer Causes Control. 2003;14(8):773-785. doi:10.1023/a:1026349702909</mixed-citation><mixed-citation xml:lang="en">Mack WJ, Preston-Martin S, Dal Maso L, et al. A pooled analysis of case-control studies of thyroid cancer: cigarette smoking and consumption of alcohol, coffee, and tea. Cancer Causes Control. 2003;14(8):773-785. doi:10.1023/a:1026349702909</mixed-citation></citation-alternatives></ref><ref id="cit59"><label>59</label><citation-alternatives><mixed-citation xml:lang="ru">Negri E, Ron E, Franceschi S, et al. Risk factors for medullary thyroid carcinoma: a pooled analysis. Cancer Causes Control. 2002;13(4):365-372. doi:10.1023/a:1015263718760</mixed-citation><mixed-citation xml:lang="en">Negri E, Ron E, Franceschi S, et al. Risk factors for medullary thyroid carcinoma: a pooled analysis. Cancer Causes Control. 2002;13(4):365-372. doi:10.1023/a:1015263718760</mixed-citation></citation-alternatives></ref><ref id="cit60"><label>60</label><citation-alternatives><mixed-citation xml:lang="ru">Kabat GC, Kim MY, Wactawski-Wende J, Rohan TE. Smoking and alcohol consumption in relation to risk of thyroid cancer in postmenopausal women. Cancer Epidemiol. 2012;36(4):335-340. doi:10.1016/j.canep.2012.03.013</mixed-citation><mixed-citation xml:lang="en">Kabat GC, Kim MY, Wactawski-Wende J, Rohan TE. Smoking and alcohol consumption in relation to risk of thyroid cancer in postmenopausal women. Cancer Epidemiol. 2012;36(4):335-340. doi:10.1016/j.canep.2012.03.013</mixed-citation></citation-alternatives></ref><ref id="cit61"><label>61</label><citation-alternatives><mixed-citation xml:lang="ru">Kitahara CM, Linet MS, Beane Freeman LE, et al. Cigarette smoking, alcohol intake, and thyroid cancer risk: a pooled analysis of five prospective studies in the United States. Cancer Causes Control. 2012;23(10):1615-1624. doi:10.1007/s10552-012-0039-2</mixed-citation><mixed-citation xml:lang="en">Kitahara CM, Linet MS, Beane Freeman LE, et al. Cigarette smoking, alcohol intake, and thyroid cancer risk: a pooled analysis of five prospective studies in the United States. Cancer Causes Control. 2012;23(10):1615-1624. doi:10.1007/s10552-012-0039-2</mixed-citation></citation-alternatives></ref><ref id="cit62"><label>62</label><citation-alternatives><mixed-citation xml:lang="ru">Barbeau AM, Burda J, Siegel M. Perceived efficacy of e-cigarettes versus nicotine replacement therapy among successful e-cigarette users: a qualitative approach. Addict Sci Clin Pract. 2013 Mar 5;8(1):5. doi: 10.1186/1940-0640-8-5.</mixed-citation><mixed-citation xml:lang="en">Barbeau AM, Burda J, Siegel M. Perceived efficacy of e-cigarettes versus nicotine replacement therapy among successful e-cigarette users: a qualitative approach. Addict Sci Clin Pract. 2013 Mar 5;8(1):5. doi: 10.1186/1940-0640-8-5.</mixed-citation></citation-alternatives></ref><ref id="cit63"><label>63</label><citation-alternatives><mixed-citation xml:lang="ru">Rom O, Pecorelli A, Valacchi G, et al. Are E-cigarettes a safe and good alternative to cigarette smoking? Ann N Y Acad Sci. 2015 Mar;1340:65-74. doi: 10.1111/nyas.12609.</mixed-citation><mixed-citation xml:lang="en">Rom O, Pecorelli A, Valacchi G, et al. Are E-cigarettes a safe and good alternative to cigarette smoking? Ann N Y Acad Sci. 2015 Mar;1340:65-74. doi: 10.1111/nyas.12609.</mixed-citation></citation-alternatives></ref><ref id="cit64"><label>64</label><citation-alternatives><mixed-citation xml:lang="ru">Grana R, Benowitz N, Glantz SA. E-cigarettes: a scientific review. Circulation. 2014 May 13;129(19):1972-86. doi: 10.1161/CIRCULATIONAHA.114.007667. PMID: 24821826; PMCID: PMC4018182.</mixed-citation><mixed-citation xml:lang="en">Grana R, Benowitz N, Glantz SA. E-cigarettes: a scientific review. Circulation. 2014 May 13;129(19):1972-86. doi: 10.1161/CIRCULATIONAHA.114.007667. PMID: 24821826; PMCID: PMC4018182.</mixed-citation></citation-alternatives></ref><ref id="cit65"><label>65</label><citation-alternatives><mixed-citation xml:lang="ru">Valentine GW, Hefner K, Jatlow PI, et al. Impact of E-cigarettes on Smoking and Related Outcomes in Veteran Smokers With Psychiatric Comorbidity. J Dual Diagn. 2018;14(1):2-13. doi:10.1080/15504263.2017.1384877</mixed-citation><mixed-citation xml:lang="en">Valentine GW, Hefner K, Jatlow PI, et al. Impact of E-cigarettes on Smoking and Related Outcomes in Veteran Smokers With Psychiatric Comorbidity. J Dual Diagn. 2018;14(1):2-13. doi:10.1080/15504263.2017.1384877</mixed-citation></citation-alternatives></ref><ref id="cit66"><label>66</label><citation-alternatives><mixed-citation xml:lang="ru">Goniewicz ML, Knysak J, Gawron M, et al. Levels of selected carcinogens and toxicants in vapour from electronic cigarettes. Tob Control. 2014;23(2):133-139. doi:10.1136/tobaccocontrol-2012-050859</mixed-citation><mixed-citation xml:lang="en">Goniewicz ML, Knysak J, Gawron M, et al. Levels of selected carcinogens and toxicants in vapour from electronic cigarettes. Tob Control. 2014;23(2):133-139. doi:10.1136/tobaccocontrol-2012-050859</mixed-citation></citation-alternatives></ref><ref id="cit67"><label>67</label><citation-alternatives><mixed-citation xml:lang="ru">Who.int [Internet]. WORLD HEALTH ORGANIZATION: News/Urgent action needed to protect children and prevent the uptake of e-cigarettes. Available from: https://www.who.int/news/item/14-12-2023-urgent-action-needed-to-protect-children-and-prevent-the-uptake-of-e-cigarettes</mixed-citation><mixed-citation xml:lang="en">Who.int [Internet]. WORLD HEALTH ORGANIZATION: News/Urgent action needed to protect children and prevent the uptake of e-cigarettes. Available from: https://www.who.int/news/item/14-12-2023-urgent-action-needed-to-protect-children-and-prevent-the-uptake-of-e-cigarettes</mixed-citation></citation-alternatives></ref><ref id="cit68"><label>68</label><citation-alternatives><mixed-citation xml:lang="ru">Arastoo S, Haptonstall KP, Choroomi Y, et al. Acute and chronic sympathomimetic effects of e-cigarette and tobacco cigarette smoking: role of nicotine and non-nicotine constituents. Am J Physiol Heart Circ Physiol. 2020;319(2):H262-H270. doi:10.1152/ajpheart.00192.2020</mixed-citation><mixed-citation xml:lang="en">Arastoo S, Haptonstall KP, Choroomi Y, et al. Acute and chronic sympathomimetic effects of e-cigarette and tobacco cigarette smoking: role of nicotine and non-nicotine constituents. Am J Physiol Heart Circ Physiol. 2020;319(2):H262-H270. doi:10.1152/ajpheart.00192.2020</mixed-citation></citation-alternatives></ref><ref id="cit69"><label>69</label><citation-alternatives><mixed-citation xml:lang="ru">Андреева О.П., Терехов А.А. ЭЛЕКТРОННЫЕ СИГАРЕТЫ: АЛЬТЕРНАТИВА КУРЕНИЮ ИЛИ ВРЕД // Наука и образование. 2022. №2</mixed-citation><mixed-citation xml:lang="en">Andreeva O.P., Terekhov A.A. ELECTRONIC CIGARETTES: ALTERNATIVE TO SMOKING OR HARM // Nauka i Obrazovanie. 2022. №2 (in Russ.)]</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
