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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ketendo</journal-id><journal-title-group><journal-title xml:lang="ru">Клиническая и экспериментальная тиреоидология</journal-title><trans-title-group xml:lang="en"><trans-title>Clinical and experimental thyroidology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1995-5472</issn><issn pub-type="epub">2310-3787</issn><publisher><publisher-name>Endocrinology Research Centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/ket20106132-38</article-id><article-id custom-type="elpub" pub-id-type="custom">ketendo-4352</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Современные нормативы потребления йода беременными и кормящими женщинами (на примере региональных исследований)</article-title><trans-title-group xml:lang="en"><trans-title>Modern concepts about idine intake for pregnant and lacting women (by the example of regional studies)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Troshina</surname><given-names>E</given-names></name></name-alternatives><email xlink:type="simple">troshina@inbox.ru</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Sekinaeva</surname><given-names>A</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Abdulchabirova</surname><given-names>F</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib></contrib-group><pub-date pub-type="collection"><year>2010</year></pub-date><pub-date pub-type="epub"><day>15</day><month>03</month><year>2010</year></pub-date><volume>6</volume><issue>1</issue><issue-title>ТОМ 6, №1 (2010)</issue-title><fpage>32</fpage><lpage>38</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Troshina E., Sekinaeva A., Abdulchabirova F., 2010</copyright-statement><copyright-year>2010</copyright-year><copyright-holder xml:lang="ru">Troshina E., Sekinaeva A., Abdulchabirova F.</copyright-holder><copyright-holder xml:lang="en">Troshina E., Sekinaeva A., Abdulchabirova F.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.cet-endojournals.ru/jour/article/view/4352">https://www.cet-endojournals.ru/jour/article/view/4352</self-uri><abstract><p>Были предложены оптимальные нормативы профилактических доз йода для беременных и кормящих женщин. Проводилась оценка уровня ТТГ, св.Т4, АТ-ТПО, экскреции йода с мочой, а также определение объема ЩЖ при помощи УЗИ в двух группах беременных: 1-я группа (n = 161) KI (200 мкг/сут) и 2-я группа (n = 178) KI (300 мкг/сут). На фоне проведения профилактики во время беременности было отмечено достоверное увеличение медианы йодурии до 259,6 (pНН =0,00) и 120,8 мкг/л (pСм = 0,00) у беременных 2-й группы, в то время как в 1-й группе экскреция йода в моче составила 96,9 (pНН = 0,00) и 83,5 мкг/л (pСм = 0,00). На фоне проведения профилактики в период лактации в Нижнем Новгороде отмечена недостаточная концентрация йода в моче у пациенток 1-й группы, а у беременных 2-й группы сохранились нормальные показатели медианы йодурии – 88,6 и 123,2 мкг/л соответственно (p = 0,00). В Смоленске наблюдалось снижение уровня йодурии, однако в 1-й группе оно было статистически значимым (p = 0,03), медиана – 41,1 и 70,3 мкг/л у пациенток 1 и 2-й групп соответственно (p = 0,04). Медиана йодурии 100 мкг/л и более была отмечена у 10,5% женщин 2-й группы, в то время как у пациенток 1-й группы c достаточной концентрацией в моче йода выявлено не было. Следовательно, уровень йодурии в течение беременности и кормления напрямую зависит от индивидуальной йодной профилактики и является оптимальным при уровне потребления йода минимально в дозе 300 мкг/сут.</p></abstract><trans-abstract xml:lang="en"><p>The aim of this study was to offer the optimal levels of daily iodine intake during pregnancy and lactation. One-stage epidemiological survey was carried on in two cities: Nizhny Novgorod (n = 220) and Smolensk (n = 119). The pregnant women were divided into two groups: Group 1 (n = 161) – KI (200 micrograms/day) and Group 2 (n = 178) – KI (300 micrograms/day). Reearch methods included: ultrasound examination of a thyroid, urinary iodine concentration (UIC) measuring, analysis of thyroid stimulating hormone (TSH), free thyroxin (fT4), thyroperoxidase autoantibody (AT-TPO). After 3 months of iodine prophylaxis during pregnancy the median UIC increased to 259,6 (pNN = 0.00) and 120,8 µg/l (pSm = 0.00) in the 2nd group, and in the 1st group the iodine excretion in urine has compounded 96.9 (pNN = 0.00) and 83.5 µg/l (pSm = 0.00). In Nizhny Novgorod during lactation there was an insufficient concentration of iodide in urine in group 1 and in group 2 there were normal indexes of a median urinary iodine – 88.6 and 123.2 µg/l accordingly (p = 0.00). In Smolensk the median UIC was dropped, however in 1st group it was statistically significant (p = 0.03), median urinary iodine was 41.1 and 70.3 µg/l in groups 1st and 2nd accordingly (p = 0.04). The median UIC &gt;100 µg/l has been noted at 10.5% of women in the 2nd group, and in the 1st group of patients by sufficient UIC has not been detected. Consequently, the median level of urinary iodine indicate optimal iodine nutrition during pregnancy and lactation and the requirement of iodine is at least 300 µg/day.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>йодный дефицит</kwd><kwd>йодная профилактика</kwd><kwd>йододефицитные заболевания</kwd><kwd>беременные икормящие женщины</kwd></kwd-group><kwd-group xml:lang="en"><kwd>iodine deficiency</kwd><kwd>iodine prophylaxis</kwd><kwd>iodine deficiency disorders</kwd><kwd>pregnant and lactating women</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Andersson M., de Benoist B., Delange F., Zupan J. 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