ketendoКлиническая и экспериментальная тиреоидологияClinical and experimental thyroidology1995-54722310-3787Endocrinology Research Centre10.14341/ket20117257-62ketendo-4363Research ArticleСтатьиArticlesТиреоидный статус у лиц с ожирениемThyroid function in the people with obesityMustafinaS V

канд. мед. наук, старший научный сотрудник лаборатории клинико-популяционных и профилактических исследований терапевтических и эндокринных заболеваний НИИ терапии СО РАМН

-RymarO D

доктор мед. наук, ведущий научный сотрудник лаборатории клинико-популяционных и профилактических исследований терапевтических и эндокринных заболеваний НИИ терапии СО РАМН

Orymar23@gmail.comSimonovaG I

профессор, доктор мед. наук, заместитель директора НИИ терапии СО РАМН, заведующая кафедрой эпидемиологии и профилактики ХНИЗ НГМУ

-ScherbakovaL V

старший научный сотрудник лаборатории клинико-популяционных и профилактических исследований терапевтических и эндокринных заболеваний НИИ терапии СО РАМН

-20111506201172ТОМ 7, №2 (2011)5762Copyright © Mustafina S.V., Rymar O.D., Simonova G.I., Scherbakova L.V., 20112011Mustafina S.V., Rymar O.D., Simonova G.I., Scherbakova L.V.Mustafina S.V., Rymar O.D., Simonova G.I., Scherbakova L.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.cet-endojournals.ru/jour/article/view/4363

В ходе исследования предстояло определить связь уровней тиреотропного гормона (ТТГ), общего тироксина с показателями индекса массы тела и окружностью талии у мужчин и женщин с избыточной массой тела и ожирением. Данное исследование было выполнено в рамках проекта HAPIEЕ. Проанализирована популяционная подвыборка 280 человек (125 мужчин (44,6%) и 155 женщин (55,4%)). В объединенной группе лиц со II и III степенью ожирения (индекс массы тела35 кг/м2 и более) определены более высокие значения ТТГ. У женщин индекс массы тела 30 кг/м2 и более и абдоминальным ожирением (по критериям NCEP-АТР III, 2001) средние значения общего тироксина достоверно выше, чем в группе с нормальной и избыточной массой тела. У мужчин, имеющих более выраженное ожирение (индекс массы тела 35 кг/м2 и более), также отмечено значимое повышение общего тироксина. В женской подвыборке, в отличие от мужской, определена слабая положительная корреляционная связь значений общего тироксина с показателями окружности талии

The aim of this study is to identify the association of thyroid stimulating hormone and thyroxin levels with body mass index (BMI) and waste circumference in men and women with overweight and obesity. Current study was performed within the HAPIEE. The sample of 280 subjects (125 men (44.6%) and 155 women (55.4%)) was analyzed. Thyroid stimulating hormone level was high in integrated subsample with II and III obesity degree (body mass index ≥35 kg/m2). Average levels of general thyroxin were significantly higher in abdominal obese women with body mass index ≥30 (according to NCEP-АТР III, 2001), than in subjects with normal weight and overweight. Significant decrease of general thyroxin was detected in men with gross obesity (body mass index ≥35 kg/m2). In comparison with men women have positive correlation between general thyroxin level and waist circumference.

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The authors declare that there are no conflicts of interest present.