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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ketendo</journal-id><journal-title-group><journal-title xml:lang="ru">Клиническая и экспериментальная тиреоидология</journal-title><trans-title-group xml:lang="en"><trans-title>Clinical and experimental thyroidology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1995-5472</issn><issn pub-type="epub">2310-3787</issn><publisher><publisher-name>Endocrinology Research Centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/ket20106251-56</article-id><article-id custom-type="elpub" pub-id-type="custom">ketendo-4383</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Состояние щитовидной железы у больных с хронической почечной недостаточностью на программном гемодиализе</article-title><trans-title-group xml:lang="en"><trans-title>The condition of thyroid gland in patients with chronic renal failure on a long-term hemodialysis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Dogadin</surname><given-names>S A</given-names></name></name-alternatives><email xlink:type="simple">dogadin@online.ru</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ivlieva</surname><given-names>E S</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ivliev</surname><given-names>S V</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib></contrib-group><pub-date pub-type="collection"><year>2010</year></pub-date><pub-date pub-type="epub"><day>15</day><month>06</month><year>2010</year></pub-date><volume>6</volume><issue>2</issue><issue-title>ТОМ 6, №2 (2010)</issue-title><fpage>51</fpage><lpage>56</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Dogadin S.A., Ivlieva E.S., Ivliev S.V., 2010</copyright-statement><copyright-year>2010</copyright-year><copyright-holder xml:lang="ru">Dogadin S.A., Ivlieva E.S., Ivliev S.V.</copyright-holder><copyright-holder xml:lang="en">Dogadin S.A., Ivlieva E.S., Ivliev S.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.cet-endojournals.ru/jour/article/view/4383">https://www.cet-endojournals.ru/jour/article/view/4383</self-uri><abstract><p>В ходе исследования предстояло изучить состояние щитовидной железы и тиреоидного статуса у больных хронической почечной недостаточностью, находящихся на программном гемодиализе. Обследовано 234 пациента с хронической почечной недостаточностью (105 мужчин и 129 женщин), находящихся на лечении гемодиализом от 1 до 167 мес, проживающих в городах Восточной Сибири. Проводились сонография щитовидной железы, исследование в крови тиротропина, свободных тироксина и трйодтиронина и антител к тиреоидной пероксидазе. Среди обследованных у 60 человек (25,4%) впервые диагностированы заболевания щитовидной железы (аутоиммунный тиреоидит без нарушения функции и с субклиническим гипотиреозом, диффузный эутироидный зоб), у 102 пациентов (43,6%) тиреоидной патологии не выявлено, у 39 больных (16,7%) определен синдром эутиреоидной патологии тип 1 или 2.</p></abstract><trans-abstract xml:lang="en"><p>To lean the condition of thyroid gland and thyroid function in patients with chronic renal failure on a hemodialysis. A total of 234 patients (105 males and 129 females) with chronic renal failure who are being treated by a long-term hemodialysis from 1 to 167 months, living in different city of Eastern Siberia were examined. All patients included in the study have ultrasonografic scan of thyroid. Free thyroid hormones, thyrotropin and thyroid peroxidase antibodies blood levels were determined. Among the examined cases in 60 (25.4%) was diagnosed thyroid disease (autoimmune thyroiditis without dysfunction, subclinical hypothyroidism, nontoxic diffuse or nodular goiter) for the first time. In 102 (43.6%) of cases the thyroid disease has not revealed, in 39 (16.7%) euthyroid sick syndrome type 1 or 2 was determined.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>хроническая почечная недостаточность</kwd><kwd>программный гемодиализ</kwd><kwd>щитовидная железа</kwd><kwd>заболевания</kwd><kwd>синдром эутиреоидной патологии</kwd><kwd>жители Восточной Сибири</kwd></kwd-group><kwd-group xml:lang="en"><kwd>chronic renal failure</kwd><kwd>long-term hemodialysis</kwd><kwd>thyroid gland</kwd><kwd>diseases</kwd><kwd>euthyroid sick syndrome</kwd><kwd>inhabitants of Eastern Siberia</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Бикбов Б.Т. Выживаемость и факторы риска неблагоприятных исходов у больных на программном гемодиализе // Нефрология и диализ. 2004. Т. 6. №4. С. 280–296.</mixed-citation><mixed-citation xml:lang="en">Бикбов Б.Т. Выживаемость и факторы риска неблагоприятных исходов у больных на программном гемодиализе // Нефрология и диализ. 2004. Т. 6. №4. С. 280–296.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Стокинг Ж.-Р. Синдром эутиреоидной патологии: современное состояние проблемы в кн.: Болезни щитовидной железы: Пер с англ. / Под ред. Браверманна Л.И. М., 2000. С. 78–91.</mixed-citation><mixed-citation xml:lang="en">Стокинг Ж.-Р. Синдром эутиреоидной патологии: современное состояние проблемы в кн.: Болезни щитовидной железы: Пер с англ. / Под ред. Браверманна Л.И. М., 2000. С. 78–91.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Зайратьянц О.В. Эпидемиология и этиологическая структура узлового зоба по данным аутопсий http://thyronet.rusmedserv.com/th_spec/thyr-5-6-02-8.html</mixed-citation><mixed-citation xml:lang="en">Зайратьянц О.В. Эпидемиология и этиологическая структура узлового зоба по данным аутопсий http://thyronet.rusmedserv.com/th_spec/thyr-5-6-02-8.html</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Савченков М.Ф., Селятицкая В.Г., Колесников С.И. и др. Йод и здоровье населения Сибири / Новосибирск: Наука, 2002.</mixed-citation><mixed-citation xml:lang="en">Савченков М.Ф., Селятицкая В.Г., Колесников С.И. и др. Йод и здоровье населения Сибири / Новосибирск: Наука, 2002.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Панченкова Л.А, Трошина Е.А, Юркова Т.Е. Синдром эутиреоидной патологии в клинике внутренних болезней. // Рос. мед. вести. 2003. №1. C.11–15.</mixed-citation><mixed-citation xml:lang="en">Панченкова Л.А, Трошина Е.А, Юркова Т.Е. Синдром эутиреоидной патологии в клинике внутренних болезней. // Рос. мед. вести. 2003. №1. C.11–15.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Avasthi G., Malhotra S., Narang A.P.S., Sengupta S. Study of thyroid function in patients of chronic renal failure // Ind. J. Nephrol. 2001. V. 11. P. 165–169</mixed-citation><mixed-citation xml:lang="en">Avasthi G., Malhotra S., Narang A.P.S., Sengupta S. Study of thyroid function in patients of chronic renal failure // Ind. J. Nephrol. 2001. V. 11. P. 165–169</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Bando Y., Ushiogi Y., Okafuji K. et al. Non-autoimmune primary hypothyroidism in diabetic and non-diabetic chronic renal dysfunction // Exp. Clin. Endocrinol. Diabetes. 2002. V. 110. P. 408–415.</mixed-citation><mixed-citation xml:lang="en">Bando Y., Ushiogi Y., Okafuji K. et al. Non-autoimmune primary hypothyroidism in diabetic and non-diabetic chronic renal dysfunction // Exp. Clin. Endocrinol. Diabetes. 2002. V. 110. P. 408–415.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Chonchol M., Lippi G., Salvagno G. et al. // Clin. J. Am. Soc. Nephrol. 2008. V. 3. P. 1296–1300.</mixed-citation><mixed-citation xml:lang="en">Chonchol M., Lippi G., Salvagno G. et al. // Clin. J. Am. Soc. Nephrol. 2008. V. 3. P. 1296–1300.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Chonchol M., Lippi G., Salvagno Gi. et al. Prevalence of Subclinical Hypothyroidism in Patients with Chronic Kidney Disease // Clin. J. Am. Soc. Nephrol. 2008. V. 3. P. 1296–1300.</mixed-citation><mixed-citation xml:lang="en">Chonchol M., Lippi G., Salvagno Gi. et al. Prevalence of Subclinical Hypothyroidism in Patients with Chronic Kidney Disease // Clin. J. Am. Soc. Nephrol. 2008. V. 3. P. 1296–1300.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Chopra I.J., Hershman J.M., Pardridge W.M., Nicoloff J.T. Thyroid function in nonthyroidal illnesses // Ann. Intern. Med. 1983. V. 98. P. 946–957.</mixed-citation><mixed-citation xml:lang="en">Chopra I.J., Hershman J.M., Pardridge W.M., Nicoloff J.T. Thyroid function in nonthyroidal illnesses // Ann. Intern. Med. 1983. V. 98. P. 946–957.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Hegedüs L., Andersen J.R., Poulsen L.R. et al. Thyroid gland volume and serum concentrations of thyroid hormones in chronic renal failure // Nephron. 1985. V. 40. P. 171–174.</mixed-citation><mixed-citation xml:lang="en">Hegedüs L., Andersen J.R., Poulsen L.R. et al. Thyroid gland volume and serum concentrations of thyroid hormones in chronic renal failure // Nephron. 1985. V. 40. P. 171–174.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Iglesias P., Díez J.J. Thyroid dysfunction and kidney disease // Eur. J. Endocrinol. 2009. V. 160. P. 503–515.</mixed-citation><mixed-citation xml:lang="en">Iglesias P., Díez J.J. Thyroid dysfunction and kidney disease // Eur. J. Endocrinol. 2009. V. 160. P. 503–515.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Kang E.W., Nam J.Y., Yoo T.H. et al. Clinical implications of subclinical hypothyroidism in continuous ambulatory peritoneal dialysis patients // Am. J. Nephrol. 2008. V. 28. P. 908–913.</mixed-citation><mixed-citation xml:lang="en">Kang E.W., Nam J.Y., Yoo T.H. et al. Clinical implications of subclinical hypothyroidism in continuous ambulatory peritoneal dialysis patients // Am. J. Nephrol. 2008. V. 28. P. 908–913.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Kaptein E.M. Thyroid hormone metabolism and thyroid diseases in chronic renal failure // Endocrin. Rev. 1996. V. 1. P. 45–63.</mixed-citation><mixed-citation xml:lang="en">Kaptein E.M. Thyroid hormone metabolism and thyroid diseases in chronic renal failure // Endocrin. Rev. 1996. V. 1. P. 45–63.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Kaptein E.M., Quion-Verde H., Chooljian C.J. et al. The thyroid in end-stage renal disease // Medicine (Baltimore). 1988. V. 67. P. 187–197.</mixed-citation><mixed-citation xml:lang="en">Kaptein E.M., Quion-Verde H., Chooljian C.J. et al. The thyroid in end-stage renal disease // Medicine (Baltimore). 1988. V. 67. P. 187–197.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Kutlay S., Atli T., Koseogullari O. Thyroid disorders in hemodialysis patients in an iodine-deficient community // Artif.Organs. 2005. V. 4. P. 329–332.</mixed-citation><mixed-citation xml:lang="en">Kutlay S., Atli T., Koseogullari O. Thyroid disorders in hemodialysis patients in an iodine-deficient community // Artif.Organs. 2005. V. 4. P. 329–332.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Lebkowska U., Malyszko J., Mysliwiec M. Thyroid function and morphology in kidney transplant recipients, hemodialyzed, and peritoneal dialyzed patients // Transplant Proc. 2003. V. 8. P. 2945–2948.</mixed-citation><mixed-citation xml:lang="en">Lebkowska U., Malyszko J., Mysliwiec M. Thyroid function and morphology in kidney transplant recipients, hemodialyzed, and peritoneal dialyzed patients // Transplant Proc. 2003. V. 8. P. 2945–2948.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Lechan R.M. The dilemma of the nonthyroidal illness syndrome // Acta Biomed. 2008. V. 3. P. 165–171.</mixed-citation><mixed-citation xml:lang="en">Lechan R.M. The dilemma of the nonthyroidal illness syndrome // Acta Biomed. 2008. V. 3. P. 165–171.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Lim V.S. Thyroid function in patients with chronic renal failure // Am. J. Kidney Dis. 2001.V. 4. Suppl. 1. P. 80–84.</mixed-citation><mixed-citation xml:lang="en">Lim V.S. Thyroid function in patients with chronic renal failure // Am. J. Kidney Dis. 2001.V. 4. Suppl. 1. P. 80–84.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Lin C.C., Chen T.W., Ng Y.Y. et al. Thyroid dysfunction and nodular goiter in hemodialysis and peritoneal dialysis patients // Perit. Dial. Int. 1998. V. 18. P. 516.</mixed-citation><mixed-citation xml:lang="en">Lin C.C., Chen T.W., Ng Y.Y. et al. Thyroid dysfunction and nodular goiter in hemodialysis and peritoneal dialysis patients // Perit. Dial. Int. 1998. V. 18. P. 516.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Nelson J.C., Weiss R.M., Wilcox R.B. Underestimates of serum free thyroxine (T4) concentrations by free T4 immunoassays // J. Clin. Endocrinol. Metab. 1994. V.1. P. 76–79.</mixed-citation><mixed-citation xml:lang="en">Nelson J.C., Weiss R.M., Wilcox R.B. Underestimates of serum free thyroxine (T4) concentrations by free T4 immunoassays // J. Clin. Endocrinol. Metab. 1994. V.1. P. 76–79.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Niemczyk S., WoŸniacki L. Thyroid hormones disturbances in critical ill patients-low T3 syndrome // Pol. Arch. Med. Wewn. 2005. V. 6. P. 1260–1266.</mixed-citation><mixed-citation xml:lang="en">Niemczyk S., WoŸniacki L. Thyroid hormones disturbances in critical ill patients-low T3 syndrome // Pol. Arch. Med. Wewn. 2005. V. 6. P. 1260–1266.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Sanai T., Inoue T., Okamura K. et al. Reversible primary hypothyroidism in Japanese patients undergoing maintenance hemodialysis // Clin. Nephrol. 2008. V. 69. P. 107–113.</mixed-citation><mixed-citation xml:lang="en">Sanai T., Inoue T., Okamura K. et al. Reversible primary hypothyroidism in Japanese patients undergoing maintenance hemodialysis // Clin. Nephrol. 2008. V. 69. P. 107–113.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Sapin R., Schlienger J.L., Kaltenbach G. et al. Determination of free triiodothyronine by six different methods in patients with nonthyroidal illness and in patients treated with amiodarone // J. Ann. Clin. Biochem. 1995. V. 32. Pt 3. P. 314–324.</mixed-citation><mixed-citation xml:lang="en">Sapin R., Schlienger J.L., Kaltenbach G. et al. Determination of free triiodothyronine by six different methods in patients with nonthyroidal illness and in patients treated with amiodarone // J. Ann. Clin. Biochem. 1995. V. 32. Pt 3. P. 314–324.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Sato K., Okamura K., Yoshinary M. et al. Reversible primary hypothyroidism and elevated serum iodine level in patients with renal dysfunction // Acta Endocrinol. (Copenh). 1992. V. 126. P. 253–259.</mixed-citation><mixed-citation xml:lang="en">Sato K., Okamura K., Yoshinary M. et al. Reversible primary hypothyroidism and elevated serum iodine level in patients with renal dysfunction // Acta Endocrinol. (Copenh). 1992. V. 126. P. 253–259.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Valentin M., Bueno B., Guttierrez E. et al. Membranoproliferative glomerulonephritis associated with autoimmune thyroiditis // Nefrologia. 2004. V. 24. Suppl. 3. P. 3–48.</mixed-citation><mixed-citation xml:lang="en">Valentin M., Bueno B., Guttierrez E. et al. Membranoproliferative glomerulonephritis associated with autoimmune thyroiditis // Nefrologia. 2004. V. 24. Suppl. 3. P. 3–48.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Zoccali C., Mallamaci F., Tripepi G. et al. Low triiodothyronine and survival in end-stage renal disease // Kidney International. 2006. V. 70. P. 523–528.</mixed-citation><mixed-citation xml:lang="en">Zoccali C., Mallamaci F., Tripepi G. et al. Low triiodothyronine and survival in end-stage renal disease // Kidney International. 2006. V. 70. P. 523–528.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
