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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ketendo</journal-id><journal-title-group><journal-title xml:lang="ru">Клиническая и экспериментальная тиреоидология</journal-title><trans-title-group xml:lang="en"><trans-title>Clinical and experimental thyroidology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1995-5472</issn><issn pub-type="epub">2310-3787</issn><publisher><publisher-name>Endocrinology Research Centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/ket20139147-50</article-id><article-id custom-type="elpub" pub-id-type="custom">ketendo-6347</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Клинический случай аутоиммунного полигландулярного синдрома второго типа</article-title><trans-title-group xml:lang="en"><trans-title>A clinical case of autoimmune polyglandular syndrome type 2</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Petunina</surname><given-names>N A</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор мед. наук, профессор, зав. кафедрой эндокринологии Первого МГМУ им. И.М. Сеченова</p></bio><email xlink:type="simple">napetunina@mail.ru</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Trukhina</surname><given-names>L V</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. мед. наук, доцент кафедры эндокринологии Первого МГМУ им. И.М. Сеченова</p></bio><email xlink:type="simple">-</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Martirosyan</surname><given-names>N S</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-эндокринолог</p></bio><email xlink:type="simple">-</email></contrib></contrib-group><pub-date pub-type="collection"><year>2013</year></pub-date><pub-date pub-type="epub"><day>15</day><month>03</month><year>2013</year></pub-date><volume>9</volume><issue>1</issue><issue-title>ТОМ 39, №1 (2013)</issue-title><fpage>47</fpage><lpage>50</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Petunina N.A., Trukhina L.V., Martirosyan N.S., 2013</copyright-statement><copyright-year>2013</copyright-year><copyright-holder xml:lang="ru">Petunina N.A., Trukhina L.V., Martirosyan N.S.</copyright-holder><copyright-holder xml:lang="en">Petunina N.A., Trukhina L.V., Martirosyan N.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.cet-endojournals.ru/jour/article/view/6347">https://www.cet-endojournals.ru/jour/article/view/6347</self-uri><abstract><p>В статье приводится клиническое наблюдение молодой женщины с аутоиммунным полигландулярным синдромом 2го типа, представленным первичной недостаточностью коры надпочечников и нарушением функции щитовидной железы. В ходе течения заболевания произошло изменение функциональной активности щитовидной железы со сменой гипотиреоза на тиреотоксикоз, что стало причиной резкой декомпенсации надпочечниковой недостаточности.</p></abstract><trans-abstract xml:lang="en"><p>This article describes the case of a young woman with autoimmune polyglandular syndrome type 2, presented by the primary adrenal insufficiency and thyroid dysfunction. In the course of the disease there was a change of the thyroid functional activity from hypothyroidism to hyperthyroidism, which led to adrenal insufficiency decompensation.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>аутоиммунный полигландулярный синдром 2го типа</kwd><kwd>гипотиреоз</kwd><kwd>гипертиреоз</kwd><kwd>надпочечниковая недоста точность</kwd></kwd-group><kwd-group xml:lang="en"><kwd>autoimmune polyglandular syndrome type 2</kwd><kwd>hypothyroidism</kwd><kwd>hyperthyroidism</kwd><kwd>adrenal insufficiency</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Bhandarkar S.D., Retnam V.J. Hyperthyroidism following hypothyroidism. J. Postgrad. Med. 1980; 26 (1): 90–94.</mixed-citation><mixed-citation xml:lang="en">Bhandarkar S.D., Retnam V.J. Hyperthyroidism following hypothyroidism. J. Postgrad. 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