ketendoКлиническая и экспериментальная тиреоидологияClinical and experimental thyroidology1995-54722310-3787Endocrinology Research Centre10.14341/ket2015233-37ketendo-7611Research ArticleСтатьиArticlesВлияние субклинического тиреотоксикоза на сердечно-сосудистую системуInfluence of subclinical hyperthyroidism on the cardiovascular systemДемидоваТатьяна ЮльевнаDemidovaT Y

д.м.н., профессор кафедры эндокринологии и диабетологии ГБОУ ДПО РМАПО Минздрава России, Москва.

-ДроздоваИрина НиколаевнаDrozdovaI N

аспирант кафедры эндокринологии и диабетологии ГБОУ ДПО РМАПО Минздрава России, Москва.

docdrozdova@yandex.ruГБОУ ДПО “Российская медицинская академия последипломного образования” Минздрава России, МоскваRussian Medical Academy of Postgraduate Education, Moscow, Russian Federation201515062015112ТОМ 11, №2 (2015)3337Copyright © Демидова Т.Ю., Дроздова И.Н., 20152015Демидова Т.Ю., Дроздова И.Н.Demidova T.Y., Drozdova I.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.cet-endojournals.ru/jour/article/view/7611

ГБОУ ДПО “Российская медицинская академия последипломного образования” Минздрава России, Москва Субклинический тиреотоксикоз характеризуется сниженным или неопределяемым уровнем тиреотропного гормона в сочетании с нормальными уровнями тироксина и трийодтиронина. Клинические проявления субклинического тиреотоксикоза являются малоизученными. Субклинический тиреотоксикоз оказывает несколько эффектов на сердечно-сосудистую систему, например, увеличение частоты сердечных сокращений, массы левого желудочка. Экспериментальные исследования выявили связь между субклиническим тиреотоксикозом и ишемической болезнью сердца, частотой возникновения фибрилляции предсердий и сердечной дисфункции.

Subclinical hyperthyroidism occurs when the serum TSH is below the lower limit of the reference range and the free T4 and T3 concentrations are normal. Тhe clinical significance of subclinical hyperthyroidism is much debated. Subclinical hyperthyroidism has been associated with several biological effects on cardiovascular system, such as increased heart rate, left ventricular mass. Observational studies have reported an association between subclinical hyperthyroidism and coronary heart disease, incident atrial fibrillation, and cardiac dysfunction.

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The authors declare that there are no conflicts of interest present.