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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ketendo</journal-id><journal-title-group><journal-title xml:lang="ru">Клиническая и экспериментальная тиреоидология</journal-title><trans-title-group xml:lang="en"><trans-title>Clinical and experimental thyroidology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1995-5472</issn><issn pub-type="epub">2310-3787</issn><publisher><publisher-name>Endocrinology Research Centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/ket2017257-61</article-id><article-id custom-type="elpub" pub-id-type="custom">ketendo-9352</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Письма в редакцию</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Letters to the Editor</subject></subj-group></article-categories><title-group><article-title>“Паттерновый подход”, или поиск новых шаблонов. Комментарии к статье “Изучение значимости тиреоглобулина в крови в качестве биомаркера при оценке тяжести йододефицитных состояний в Узбекистане”</article-title><trans-title-group xml:lang="en"><trans-title>“Pattern approach” or search for new templates. Respond to the article “Evaluating of significance of thyroglobulin (Tg) level in blood as a biomarker of iodine deficiency disorders severity in Uzbekistan”</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5634-7877</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мельниченко</surname><given-names>Галина Афанасьевна</given-names></name><name name-style="western" xml:lang="en"><surname>Mel'nichenko</surname><given-names>Galina A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор, академик РАН</p></bio><bio xml:lang="en"><p>MD, PhD, Professor</p></bio><email xlink:type="simple">teofrast2000@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Маколина</surname><given-names>Наталья Павловна</given-names></name><name name-style="western" xml:lang="en"><surname>Makolina</surname><given-names>Natalia P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н.</p></bio><bio xml:lang="en"><p>PhD</p></bio><email xlink:type="simple">natamcolina@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4382-0514</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Михина</surname><given-names>Маргарита Сергеевна</given-names></name><name name-style="western" xml:lang="en"><surname>Mikhina</surname><given-names>Margarita S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>н.с.</p></bio><email xlink:type="simple">docmikhina@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6388-1544</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Платонова</surname><given-names>Надежда Михайловна</given-names></name><name name-style="western" xml:lang="en"><surname>Platonova</surname><given-names>Nadezhda M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н.</p></bio><bio xml:lang="en"><p>PhD</p></bio><email xlink:type="simple">doc-platonova@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8520-8702</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Трошина</surname><given-names>Екатерина Анатольевна</given-names></name><name name-style="western" xml:lang="en"><surname>Troshina</surname><given-names>Ekaterina A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор РАН</p></bio><bio xml:lang="en"><p>MD, PhD, Professor</p></bio><email xlink:type="simple">troshina@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>&lt;p&gt;ФГБУ &amp;ldquo;Национальный медицинский исследовательский центр эндокринологии&amp;rdquo; Министерства здравоохранения&amp;nbsp;Российской Федерации&lt;/p&gt;</institution><country>Россия</country></aff><aff xml:lang="en"><institution>&lt;p&gt;Endocrinology Research Centre&lt;/p&gt;</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>&lt;p&gt;ФГБУ &amp;ldquo;Национальный медицинский исследовательский центр эндокринологии&amp;rdquo; Министерства здравоохранения Российской Федерации&lt;/p&gt;</institution><country>Россия</country></aff><aff xml:lang="en"><institution>&lt;p&gt;Endocrinology Research Centre&lt;/p&gt;</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>11</day><month>10</month><year>2017</year></pub-date><volume>13</volume><issue>2</issue><fpage>57</fpage><lpage>61</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Мельниченко Г.А., Маколина Н.П., Михина М.С., Платонова Н.М., Трошина Е.А., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Мельниченко Г.А., Маколина Н.П., Михина М.С., Платонова Н.М., Трошина Е.А.</copyright-holder><copyright-holder xml:lang="en">Mel'nichenko G.A., Makolina N.P., Mikhina M.S., Platonova N.M., Troshina E.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.cet-endojournals.ru/jour/article/view/9352">https://www.cet-endojournals.ru/jour/article/view/9352</self-uri><abstract><p>Наука никогда не остановится в своем поиске новых решений. Процесс исследования и прогнозирования научными теориями есть процесс выявления и управления паттернами – совокупностями повторяющихся шаблонов, устойчивыми комбинациями и последовательностями.</p><p>На протяжении многих лет проблема йодного дефицита сохраняет свою значимость для мирового здравоохранения. Несмотря на все предпринимаемые меры по ликвидации данной катастрофы, в настоящее время оптимизировать ее диагностику и лечение не удается, таким образом, ранее опубликованная в журнале “Клиническая и экспериментальная тиреоидология” работа “Изучение значимости тиреоглобулина в крови в качестве биомаркера при оценке тяжести йододефицитных состояний в Узбекистане” является невероятно актуальной и, несомненно, требует детального разбора, чему и посвящена данная статья.</p></abstract><trans-abstract xml:lang="en"><p>Science will never stop in its search for new solutions. The process of investigating and predicting by scientific theories — is the process of identifying and managing patterns (sets of repetitive models, stable combinations and sequences).</p><p>Over the years, the problem of iodine deficiency remains important for global health. Despite all the measures have been taken to eliminate this disease, now it is not possible to optimize iodine deficiency diagnosis and treatment all over the world. So, previously published in Clinical and experimental thyroidology journal article “Evaluating of significance of thyroglobulin (Tg) level in blood as a biomarker of iodine deficiency disorders severity in Uzbekistan” is incredibly relevant and undoubtedly requires detailed analysis. The analysis and comments to provided research is the subject of current article.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>йододефицитные заболевания</kwd><kwd>йод</kwd><kwd>дефицит</kwd><kwd>тиреоглобулин</kwd></kwd-group><kwd-group xml:lang="en"><kwd>iodine deficiency disorders</kwd><kwd>iodine</kwd><kwd>deficiency</kwd><kwd>thyroglobulin</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Iodine Global Network Iodine deficiency 2015. [Интернет] Доступно по ссылке URL: http://ign.org/p142000263.html. Accessed September 16, 2015.</mixed-citation><mixed-citation xml:lang="en">Iodine Global Network Iodine deficiency 2015. [Интернет] Доступно по ссылке URL: http://ign.org/p142000263.html. 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