Radionuclide diagnostics of the thyroid gland: a 100-year history
M. V. Degtyarev,
E. S. Alyoshina,
A. A. Kharlov,
K. Yu. Slashchuk,
S. S. Serzhenko,
K. S. Nizhegorodova,
M. S. Sheremeta https://doi.org/10.14341/ket12817
Abstract
The history of radionuclide diagnostics began with the first experiments on radioactive isotopes at the beginning of the 20th century. The introduction of radioactive isotopes of iodine and technetium into thyroid diagnostics and treatment was the start of the development of all nuclear medicine and theranostics. The hardware for nuclear medicine has come a long way from simple Geiger-Muller counters to modern machines with molecular imaging capabilities PET and SPECT. Nuclear thyroidology today is an important applied tool for high-tech diagnostics and treatment of thyroid diseases.
About the Authors
M. V. Degtyarev
Endocrinology Research Centre
Russian Federation
Competing Interests:
Russian Federation
Mikhail V. Degtyarev, MD
Moscow
Competing Interests:
Авторы декларируют отсутствие явных и потенциальных конфликтов интересов, связанных с содержанием настоящей статьи.
E. S. Alyoshina
Endocrinology Research Centre
Russian Federation
Competing Interests:
Russian Federation
Yekaterina S. Alyoshina, MD
Moscow
Competing Interests:
Авторы декларируют отсутствие явных и потенциальных конфликтов интересов, связанных с содержанием настоящей статьи.
A. A. Kharlov
Endocrinology Research Centre
Russian Federation
Competing Interests:
Russian Federation
Alyona A. Kharlova, resident
11 Dm. Ulyanova street, 117292, Moscow
Competing Interests:
Авторы декларируют отсутствие явных и потенциальных конфликтов интересов, связанных с содержанием настоящей статьи.
K. Yu. Slashchuk
Endocrinology Research Centre
Russian Federation
Competing Interests:
Russian Federation
Konstantin Yu. Slashchuk, MD, PhD
Moscow
Competing Interests:
Авторы декларируют отсутствие явных и потенциальных конфликтов интересов, связанных с содержанием настоящей статьи.
S. S. Serzhenko
Endocrinology Research Centre
Russian Federation
Competing Interests:
Russian Federation
Sergei S. Serzhenko, MD
Moscow
Competing Interests:
Авторы декларируют отсутствие явных и потенциальных конфликтов интересов, связанных с содержанием настоящей статьи.
K. S. Nizhegorodova
Endocrinology Research Centre
Russian Federation
Competing Interests:
Russian Federation
Ksenia S. Nizhegorodova, MD
Moscow
Competing Interests:
Авторы декларируют отсутствие явных и потенциальных конфликтов интересов, связанных с содержанием настоящей статьи.
M. S. Sheremeta
Endocrinology Research Centre
Russian Federation
Competing Interests:
Russian Federation
Marina S. Sheremeta, MD, PhD
Moscow
Competing Interests:
Авторы декларируют отсутствие явных и потенциальных конфликтов интересов, связанных с содержанием настоящей статьи.
References
1. Rumyantsev PO, Degtyarev MV, Dzeytova DS, Trukhin AA, Slashchuk KY, t al. Thyroid scintigraphy in diagnosis of nodular and diffuse thyroid pathology. Clinical and experimental thyroidology. 2019;15(4):138-147. (In Russ.) doi: https://doi.org/10.14341/ket12240
2. IAdernaia meditsina: spravochnik dlia personala otdelenii, laboratorii i tsentrov iadernoi meditsiny : [uchebnoe posobie] / pod obshch. red. V.I. Skvortsovoi. — 2-e izd., dop. — Moskva: FGBU GNTS FMBTS im. A.I. Burnaziana FMBA Rossii, 2020. — 388 p. (In Russ.)
3. Hevesy G. The Absorption and Translocation of Lead by Plants: A Contribution to the Application of the Method of Radioactive Indicators in the Investigation of the Change of Substance in Plants. Biochem J. 1923;17(4-5):439-45. doi: https://doi.org/10.1042/bj0170439
4. Sergienko VB, Ansheles AA. Nuclear medicine and molecular imaging in clinical practice: yesterday, today and tomorrow. Terapevticheskii Arkhiv (Ter. Arkh.). 2021;93(4):357-362. (In Russ.) doi: https://doi.org/10.26442/00403660.2021.04.200673
5. Endokrinologiia: natsional’noe rukovodstvo / pod red. I.I. Dedova, G.A. Mel’nichenko. 2-e izd., pererab. i dop. Moskva: GEOTAR-Media, 2024. 1112 p. : il. (Seriia “Natsional’nye rukovodstva”) (In Russ.)
6. Becker DV, Sawin CT. Radioiodine and thyroid disease: the beginning. Seminars in Nuclear Medicine. 1996;26(3):155-164. doi: https://doi.org/10.1016/s0001-2998(96)80020-1
7. Sabouri M, Ahamed S, Asadzadeh A, et al. Thyroidiomics: An Automated Pipeline for Segmentation and Classification of Thyroid Pathologies from Scintigraphy Images. arXiv (Cornell University). 2024. doi: https://doi.org/10.48550/arxiv.2407.10336
8. Parveen HS, Karthik S, S KM. Neural harmony: revolutionizing thyroid nodule diagnosis with hybrid networks and genetic algorithms. Computer Methods in Biomechanics & Biomedical Engineering. 2024:1-18. doi: https://doi.org/10.1080/10255842.2024.2341969
9. Eisenberg RL. Radiology, an illustrated history. St. Louis. Missouri: Mosby Year Book; 1992
10. Lee Y, Alam MR, Park H, et al. Improved diagnostic accuracy of thyroid fine-needle aspiration cytology with artificial intelligence technology. Thyroid. 2024;34(6):723-734. doi: https://doi.org/10.1089/thy.2023.0384
11. Xu W, Jia X, Mei Z, et al. Generalizability and diagnostic performance of AI models for thyroid US. Radiology. 2023;307(5). doi: https://doi.org/10.1148/radiol.221157
12. Klimanov V.A. Fizika iadernoi meditsiny. CHast’ 1. Fizicheskii fundament iadernoi meditsiny, ustroistvo i osnovnye kharakteristiki gamma-kamer i kollimatorov γ-izlucheniia, odnofotonnaia emissionnaia tomografiia, rekonstruktsiia raspredelenii radionuklidov v organizme cheloveka, poluchenie radionuklidov: uchebnoe posobie / V.A. Klimanov; NIIAU MIFI. — Moskva: NIIAU MIFI, 2012. — 308 p. (In Russ.)
13. Bochkarev VV. Progress v oblasti polucheniia i proizvodstva izotopov / V.V. Bochkarev, N.E. Brezhneva, E.E. Kulish. Atomnaia energiia. 1969;26(2):106-114. (In Russ.)
14. StarGuide™ // https://www.gehealthcare.com/ URL: https://www.gehealthcare.com/products/molecularimaging/starguide?srsltid=AfmBOortjcen0WZuz7m_vDf42gZ0XJdxB2hcfx5Wnkok4cuwLbtYREPG (дата обращения: 01.04.2025)
Supplementary files
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1. Figure 1: Georg de Hevesy (1885–1966) was a chemist who won the Nobel Prize in Chemistry in 1943 for the discovery of hafnium. | |
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2. Figure 2: Image of a hyperfunctation nodule in the right lobe of the thyroid obtained on the scintillation single channel detector. | |
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3. Figure 3: H.O. Anger and his first gamma camera. | |
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4. Figure 4: Radionuclide imaging of the thyroid gland in the 1970s (left) and in the 2020s (right). | |
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5. Figure 5. StarGuide SPECT-CT system [14]. | |
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For citations:
Degtyarev M.V., Alyoshina E.S., Kharlov A.A., Slashchuk K.Yu., Serzhenko S.S., Nizhegorodova K.S., Sheremeta M.S. Radionuclide diagnostics of the thyroid gland: a 100-year history. Clinical and experimental thyroidology. 2024;20(4):20-26. (In Russ.) https://doi.org/10.14341/ket12817
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