The Features of Thyroid Diseases after Bilateral Ovarioectomy in Perimenopausal Women in the Mild Iodine Deficient Region
https://doi.org/10.14341/ket20084446-50
Abstract
The purpose: to study the features of thyroid diseases after bilateral ovarioectomy (BOE) in perimenopausal women in the mild iodine deficient region. Population study of randomly chosen 654 women at the age of 45—55 years. Among surveyed two groups were taken out: 142 BOE women before natural menopause (NM) and 143 NM women without accompanying gynecologic pathology. Thyroid-stimulating hormone, free thyroxine and autoantibodies to thyroperoxidase, thyroid and gynecologic ultrasound were investigated in both groups.
References
1. Болезни щитовидной железы: Пер. с англ. / Под ред. Л.И. Браверманна. М., 2000. С. 140—172.
2. Мельниченко Г.А., Беркетова Т.Ю., Межевитинова Е.А. и др. Клинические особенности течения менопаузы у женщин с диффузным токсическим зобом и первичным гипотиреозом // Климактерий. 2001. № 3. С. 55.
3. Пашков В.М., Лебедев В.А., Коваленко М.В. Современные представления об этиологии и патогенезе гиперпластических процессов эндометрия // Вопр. гинекол., акушер. и перинатол. 2006. №3. С. 51—59.
4. Репродуктивная эндокринология: Пер. с англ. В 2 т. / Под ред. С.С.К. Йена, Р.Б. Джаффе. М., 1998. Т. 1. С. 587—606.
5. Фадеев В.В., Мельниченко Г.А. Физиологические дозы йода и носительство антител к тиреоидной пероксидазе: открытое рандомизированное исследование // Пробл. эндокринол. 2004. № 5. С. 3—7.
6. Эндокринология: национальное руководство / Под ред. И.И. Дедова, Г.А. Мельниченко. М., 2008. С. 488—577.
7. Abech D.D., Moratelli H.B., Leite S.C., Oliveira M.C. Effects of estrogen replacement therapy on pituitary size, prolactin and thy roid-stimulating hormone concentrations in menopausal women // Gynecol. Endocrinol. 2005. V. 21. N 4. Р. 223—226.
8. de Araujo L.F., Soares J.M. Jr., Simoes R.S. et al. Effect of conjugated equine estrogens and tamoxifen administration on thyroid gland histomorphology of the rat // Clinics. 2006. V. 61. N 4. P. 321—326.
9. Banu S.K., Arosh J.A., Govindarajulu P., Aruldhas M.M. Testosterone and estradiol differentially regulate thyroid growth in Wistar rats from immature to adult age // Endocr. Res. 2001. V. 27. N 4. P. 447—463.
10. Bottner M., Christoffel J., Rimoldi G., Wuttke W. Effects of longterm treatment with resveratrol and subcutaneous and oral estradi ol administration on the pituitary-thyroid-axis // Exp. Clin. Endocrinol. Diabetes. 2006. V. 114. N 2. P. 82—90.
11. Bulow Pedersen I., Laurberg P., Knudsen N. et al. Lack of association between thyroid autoantibodies and parity in a population study argues against microchimerism as a trigger of thyroid autoimmunity // Eur. J. Endocrinol. 2006. V. 154. P. 39—45.
12. Kum S., Eren U., Sandikci M., Musal B. A histochemical investigation of different distribution of TSH cells in adenohypophsis of female and male rats // Anat. Histol. Embryol. 2006. V. 35. N 6. P. 408—411.
13. Lima L.P., Bams I.A., Lisbôa P.C. et al. Estrogen effects on thyroid iodide uptake and thyroperoxidase activity in normal and ovariectomized rats // Steroids. 2006. V. 71. N 8. P. 653—659.
14. Luoto R., Grenman S., Salonen S., Pukkala E. Increased risk of thyroid cancer among women with hysterectomies // Am. J. Obstet. Gynecol. 2003. V. 188. N 1. P. 45—48.
15. Madej A., Persson E., Lundh T., Ridderstrâle Y. Thyroid gland function in ovariectomized ewes exposed to phytoestrogens // J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 2002. V. 777. N 1—2. P. 281—287.
16. Pearce E.N. Thyroid dysfunction in perimenopausal and postmenopausal women // Menopause Int. 2007. V. 13. N 1. Р. 8—13.
17. Phillips D.I., Lazarus J.H., Butland B.K. The influence of pregnancy and reproductive span on the occurrence of autoimmune thyroiditis // Clin. Endocrinol. (Oxf). 1990. V. 32. N 3. P. 301—306.
18. Szekeres-Bartho J., Barakonyi A., Par G. et al. Progesterone as an immunomodulatory molecule // Int. Immunopharmacol. 2001. V. 1. N 6. P. 1037—1048.
19. Sosic-Jurjevic B., Filipovic B., Milosevic V. Effects of ovariectomy and chronic estradiol administration on pituitary-thyroid axis in adult rats // Life Sci. 2006. V. 79. N 9. Р 890—897.
20. Wang S.H., Myc A., Koenig R.J. et al. 2-Methoxyestradiol, an endogenous estrogen metabolite, induces thyroid cell apoptosis // Mol. Cell Endocrinol. 2000. V. 165. N 1—2. Р 163—172.
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For citations:
, The Features of Thyroid Diseases after Bilateral Ovarioectomy in Perimenopausal Women in the Mild Iodine Deficient Region. Clinical and experimental thyroidology. 2008;4(4):46-50. (In Russ.) https://doi.org/10.14341/ket20084446-50
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