From physics to medicine, fundamentalist Leonidas D. Marinelli
https://doi.org/10.14341/ket12547
Abstract
Leonidas D. Marinelli is the greatest Italian-born American radiological physicist. Thanks to his efforts, we have an idea of the effect of radiation on the body; in medical practice a unique treatment for thyroid cancer with the help of the radioisotope I131 has appeared. The article describes in detail the life path and the formation of a scientist, which deserves special attention from readers, since Marinelli came to success thanks to his own perseverance and work, despite all the difficulties and obstacles, he received a higher education in America, found a mentor in the person of Dr. Joachino File, with whom they later became colleagues, realized their potential, made many discoveries at the intersection of physics and medicine, which are relevant to this day. Special attention in this work is paid to two significant discoveries of Marinelli, these are Marinelli’s vessels, which allow registering gamma-radiation, and Marinelli’s formula, designed to calculate the therapeutic activity of I131. We analyzed all the available materials, selected, highlighted in our article various life stages and life spheres of a scientist, tried to explain the essence of his activities as much as possible.
About the Authors
D. V. Yudakov
National Research Nuclear University MEPhI (Moscow Engineering Physics Institute)
Russian Federation
Russian Federation
Danila V. Yudakov
31, Kashirskoe hwy, 115409, Moscow, Russia
eLibrary SPIN: 9299-6542
S. P. Bondarenko
Pirogov Russian National Research Medical University (RSMU)
Sofiia P. Bondarenko
Moscow
eLibrary SPIN: 8352-1085
A. A. Trukhin
Endocrinology Research Centre
Russian Federation
Russian Federation
Alexey A. Trukhin
Moscow
eLibrary SPIN: 4398-9536
References
1. Available at: https://en.wikipedia.org/wiki/Leonidas_D._Marinelli
2. Brucer M. Leonidas D. Marinelli, Ph.D. Radiology. 1975;115(2):488-489. doi: https://doi.org/10.1148/115.2.488
3. Available at: https://infogalactic.com/info/Leonidas_D._Marinelli
4. Rumiantsev PO, Korenev SV. The history of radioiodine therapy beginnings. Clinical and experimental thyroidology. 2015;11(4):51-55. (In Russ.). doi: https://doi.org/10.14341/ket2015451-55
5. Fano U. Leonidas D. Marinelli (1906-1974). Radiat Res. 1975;61(3):538-539. doi: https://doi.org/10.2307/3574129
6. Available at: https://www.orau.org/ptp/collection/Miscellaneous/marinelli.htm
7. Marinelli LD, Hill RF. In Brookhaven National Laboratory Conference Report BNL-C-5; 1948, 98 p.
8. Bruner, H.D. and Perkinson, J.D. A Comparison of Iodine-131 Counting Methods. Nucleonics October 1952, 57 p.
9. Dratz, A.F. Well-Bottom Container Improves Gamma Counting, Nucleonics August 1957, 83 p.
10. Marinelli LD. Dosage determination in the use of radioactive isotopes. J Clin Invest. 1949;28(6 Pt 1):1271-1280. doi: https://doi.org/10.1172/JCI102194
11. Available at: https://ru.wikipedia.org/wiki/АЛАРА
12. Godfrey JM. Leonidas Marinelli: Pioneer in Radiological Physics. September 2013.
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1. Figure 1. Leonidas D. Marinelli | |
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2. Figure 2. Marinelli beaker (original version) | |
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3. Figure 3. Marinelli beaker (laboratory version). | |
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4. Figure 4. Diagram of the Marinelli vessel. | |
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Review
For citations:
Yudakov D.V., Bondarenko S.P., Trukhin A.A. From physics to medicine, fundamentalist Leonidas D. Marinelli. Clinical and experimental thyroidology. 2021;17(4):21-25. (In Russ.) https://doi.org/10.14341/ket12547
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