Imbalance of the “ligandreceptor” tumor necrosis factor αsystem and TNFRI expression in thyroid tissue in patients with Graves' disease
https://doi.org/10.14341/ket20139356-65
Abstract
The aim of the study was to examine the system of tumor necrosis factor α(TNFα), depending on the functional and morphological outcome of Graves’ disease (GD). It has been shown that activation of TNFαis associated with a “soft” and “benign” clinical course of GD and appearance of morphological markers of autoimmune thyroiditis (Hurthlecells transformation of thyroid epithelium).
About the Authors
T Saprinakand. med. nauk, dotsent kafedry endokrinologii i diabetologii GBOU VPO SibGMU
T Prokhorenko
assistent kafedry molekulyarnoy meditsiny i klinicheskoy laboratornoy diagnostiki GBOU VPO SibGMU
S Martynova
vrach-endokrinolog kliniki endokrinologii GBOU VPO SibGMU
A Dzyuman
kand. med. nauk, dotsent kafedry morfologii i obshchey patologii, NOTs “Innovatsionnye tekhnologii v morfologii” GBOU VPO SibGMU
A Zima
doktor med. nauk, professor kafedry fundamental'nykh osnov klinicheskoy meditsiny GBOU VPO SibGMU
O Popov
doktor med. nauk, professor, zav. klinikoy obshchey khirurgii GBOU VPO SibGMU, pofessor kafedry obshchey khirurgii
I Khlusov
doktor med. nauk, professor kafedry morfologii i obshchey patologii, prorektor po uchebnoy rabote NOTs “Innovatsionnye tekhnologii v morfologii” GBOU VPO SibGMU
V Latipova
kand. med. nauk, dotsent kafedry endokrinologii i diabetologii GBOU VPO SibGMU
N Ryazantseva
doktor med. nauk, professor, zav. kafedroy molekulyarnoy meditsiny i klinicheskoy laboratornoy diagnostiki GBOU VPO SibGMU, prorektor po strategicheskomu razvitiyu, innovatsionnoy politike i nauke NOTs “Biosovmestimye materialy i bioinzheneriya” pri NI TPU, SibGMU i IFPM SO RAN
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Review
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, , , , , , , , Imbalance of the “ligandreceptor” tumor necrosis factor αsystem and TNFRI expression in thyroid tissue in patients with Graves' disease. Clinical and experimental thyroidology. 2013;9(3):56-65. (In Russ.) https://doi.org/10.14341/ket20139356-65
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