Preview

Clinical and experimental thyroidology

Advanced search

Assessment of iodine status among school age children and pregnant women of Belarus in 2017–2018

https://doi.org/10.14341/ket9732

Abstract

Background. Despite the measures taken by the Government of Belarus, the problem of iodine deficiency among the population remains actual.


Aims. To determine iodine sufficiency in children and pregnant women living in Belarus.


Materials and methods. The study included 873 schoolchildren aged 9–12 years of both sexes, of which 650 children were in regular schools, and the remaining children in boarding schools. A separate group consisted of 700 practically healthy pregnant women (during gestation from 16 to 36 weeks). Questioning, determination of urinary iodine concentration and thyroid volume with ultrasound was carried out.


Results. Urine iodine median was 191 µg/L in the 873 children in 16 regions of Belarus. Thyroid volume corresponds to the normative values in children. According to the survey, 81% of households used iodized salt, constantly – 46%. Indicator of iodine sufficiency of 700 pregnant women (median urinary iodine concentration was 121 µg /l) is a non-optimal for this population group.


Conclusions. Currently adequate iodine supplementation in school age children has been achieved. The prevalence of thyroid gland diseases caused by iodine deficiency in children decreased significantly. In pregnant women iodine supply is still insufficient.

About the Authors

Tatiana V. Mokhort

Belarusian State Medical University


Belarus

MD, PhD, Professor



Sergei V. Petrenko

International Sakharov Environmental University


Belarus

PhD



Boris Y. Leushev

International Sakharov Environmental University


Belarus


Ekaterina V. Fedorenko

Republican Centre for Hygiene, Epidemiology and Public Health


Belarus

PhD, Associated Professor



Natalia D. Kolomiets

Belarusian Medical Academy of Post-graduate Education


Belarus

PhD, Professor



Alena G. Mokhort

Belarusian Medical Academy of Post-graduate Education


Belarus

PhD, MD



References

1. Петренко С.В., Мохорт Т.В., Коломиец Н.Д., и др. Эффективность белорусской модели ликвидации йододефицита. // Экологический вестник (Минск). – 2016. – №3. – С. 71-74. [Petrenko SV, Mokhort TV, Kolomiets ND, et al. Effektivnost’ belorusskoy modeli likvidatsii yododefitsita. Ekologicheskiy vestnik. 2016;(3):71-74. (InRuss.)]

2. Аринчин А.Н., Гембицкий М., Петренко С.В., и др. Зобная эндемия и йодная недостаточность у детей и подростков Республики Беларусь. // Здравоохранение. – 2000. – №11. – С. 25-30. [Arinchin AN, Gembitskii M, Petrenko SV et al. Zobnaya endemiya i yodnaya nedostatochnost’ u detey i podrostkov Respubliki Belarus’. Zdravookhranenie. 2000;(11):25-30. (In Russ.)]

3. Данн Д., ван дер Хаар Ф. Практическое руководство по устранению йодной недостаточности. Техническое пособие №3. – ICCIDD; 1994. [Dunn JT, van der Haar F. A practical guide to the correction of iodine deficiency. Technical manual №3. ICCIDD; 1994. (In Russ.)]

4. Дрозд В.М. Ультразвуковая диагностика патологии щитовидной железы у детей, подвергшихся радиационному воздействию в результате аварии на ЧАЭС: Автореф. дис. … д-ра мед. наук. – Минск; 1997. [Drozd VM. Ul’trazvukovaya diagnostika patologii shchitovidnoy zhelezy u detey, podvergshikhsya radiatsionnomuvozdeystviyu v rezul’tate avarii na ChAES. [dissertation]. Minsk; 1997. (In Russ.)]

5. Hatch M, Polyanskaya O, McConnell R, et al. Urinary iodine and goiter prevalence in Belarus: experience of the Belarus-American cohort study of thyroid cancer and other thyroid diseases following the Chornobyl nuclear accident. Thyroid. 2011;21(4): 429-437. doi: https://doi.org/10.1089/thy.2010.0143.

6. World Health Organization, International Council for the Control of the Iodine Deficiency Disorders, United Nations Children’s Fund. Assessment of the iodine deficiency disorders and monitoring their elimination. Geneva: WHO; 2007.

7. Moreno-Reyes R, Glinoer D, Van Oyen H, Vandevijvere S. High prevalence of thyroid disorders in pregnant women in a mildly iodine-deficient country: a population-based study. J Clin Endocrinol Metab. 2013;98(9):3694-3701. doi: https://doi.org/10.1210/jc.2013-2149.

8. Hynes KL, Otahal P, Hay I, Burgess JR. Mild iodine deficiency during pregnancy is associated with reduced educational outcomes in the offspring: 9-year follow-up of the gestational iodine cohort. J Clin Endocrinol Metab. 2013;98(5):1954-1962. doi: 10.1210/jc.2012-4249.

9. Olivares JL, Olivi GI, Verdasco C, et al. Low iodine intake during pregnancy. Endocrinologia y nutrición. 2012;59(5):326-330. doi: https://doi.org/10.1016/j.endoen.2011.12.001.

10. Bath SC, Steer CD, Golding J, et al. Effect of inadequate iodine status in UK pregnant women on cognitive outcomes in their children: results from the Avon Longitudinal Study of Parents and Children (ALSPAC). Lancet. 2013;382(9889):331-337. doi: https://doi.org/10.1016/s0140-6736(13)60436-5.

11. Caldwell KL, Pan Y, Mortensen ME, et al. Iodine status in pregnant women in the National Children’s Study and in U.S. women (15–44 years), National Health and Nutrition Examination Survey 2005-2010. Thyroid. 2013;23(8):927-937. doi: https://doi.org/10.1089/thy.2013.0012.

12. Monahan M, Boelaert K, Jolly K, et al. Costs and benefits of iodine supplementation for pregnant women in a mildly to moderately iodine-deficient population: a modelling analysis. Lancet Diabetes Endocrinoly. 2015;3(9):715-722. doi: https://doi.org/10.1016/s2213-8587(15)00212-0.

13. Альфтан Г., Мойсеёнок А., Мойсеёнок Е., и др. Недостаточность селена у населения Беларуси: технологии предупреждения и коррекции. // Наука и инновации. – 2012. – №11. – C. 62-67. [Al’ftan G, Moyseenok A, Moyseenok E, et al. Nedostatochnost’ selena u naseleniya Belarusi: tekhnologii preduprezhdeniya i korrektsii. Nauka i innovatsii. 2012;(11):62-67. (In Russ.)]

14. Gatseva PD, Argirova MD. High-nitrate levels in drinking water may be a risk factor for thyroid dysfunction in children and pregnant women living in rural Bulgarian areas. Int J Hyg Environ Health. 2008;211(5-6):555-559. doi: https://doi.org/10.1016/j.ijheh.2007.10.002.

15. Mervish NA, Pajak A, Teitelbaum SL, et al. Thyroid antagonists (perchlorate, thiocyanate, and nitrate) and childhood growth in a longitudinal study of U.S. girls. Environ Health Perspect. 2016;124(4):542-549. doi: https://doi.org/10.1289/ehp.1409309.

16. Мохорт Т.В., Коломиец Н.Д., Петренко С.В., и др. Проблема йодной обеспеченности в Республике Беларусь: результаты внедрения стратегии ликвидации йодного дефицита. // Международный эндокринологический журнал. – 2016. – №1. – С. 11-18. [Mokhort TV, Kolomiets ND, Petrenko SV, et al. Problem of iodine sufficiency in Republic of Belarus: Results of introduction of strategy to control iodine deficiency. International journal of endocrinology. 2016;(1):11-18. (In Russ.)]


Supplementary files

1. Fig. 1. Indicators of primary morbidity (new cases per 100 thousand) of simple non-toxic goiter in children from 1998 to 2017
Subject
Type Research Instrument
View (30KB)    
Indexing metadata ▾
2. Fig. 2. Dynamics of indicators of primary incidence of congenital hypothyroidism according to the results of neonatal screening from 2006 to 2017
Subject
Type Исследовательские инструменты
View (33KB)    
Indexing metadata ▾

Review

For citations:


Mokhort T.V., Petrenko S.V., Leushev B.Y., Fedorenko E.V., Kolomiets N.D., Mokhort A.G. Assessment of iodine status among school age children and pregnant women of Belarus in 2017–2018. Clinical and experimental thyroidology. 2018;14(3):149-155. (In Russ.) https://doi.org/10.14341/ket9732

Views: 1169


ISSN 1995-5472 (Print)
ISSN 2310-3787 (Online)