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Compression syndrome in giant euthyroid goiter

https://doi.org/10.14341/ket12752

Abstract

Given the widespread iodine deficiency, diffuse and diffuse nodular euthyroid goiter is an urgent problem. A large goiter needs to be highlighted both from the perspective of possible complications for the patient, including a decrease in the quality of life and compression syndrome, as well as from the perspective of the complexity of surgical treatment, given the technical complexity of the operation and the high probability of intraoperative and postoperative complications. The article describes a clinical case of a patient admitted to the endocrinology department with a diagnosis of diffuse nodular goiter of the 2nd degree for examination with complaints of a huge deforming formation of the neck contours, difficulty breathing when walking and during sleep. It is known from the anamnesis that the patient has been observed for about 10 years by an endocrinologist with nodular goiter. The patient was repeatedly offered surgical treatment, which he categorically refused. In the Department of endocrinology, the patient underwent a comprehensive examination to assess the condition and function of the thyroid gland, as well as to identify possible complications.

About the Authors

T. Yu. Demidova
Russian National Medical University. Ministry of Health of Russia

Tatiana Y. Demidova, MD, Professor

Moscow

eLibrary SPIN: 9600-9796



A. S. Kochina
Russian National Medical University. Ministry of Health of Russia
Russian Federation

Anna S. Kochina, MD, assistant

1 Ostrovityanova street, 117997 Moscow



Kh. Kh. Ibrokhimov
Russian National Medical University. Ministry of Health of Russia

Khudoyberdi Kh. Ibrokhimov, resident

Moscow



A. P. Khalilaeva
Russian National Medical University. Ministry of Health of Russia

Aygul P. Khalilaeva, resident

Moscow



References

1. Kurinova AN, Nikitina T V., Trukhina DA, et al. The formation of endocrinology in the ancient times. Problems of Endocrinology. 2022;68(1):4-7. (In Russ.). doi: https://doi.org/10.14341/probl12878

2. Alkabban FM, Patel BC. Nontoxic Goiter. 2022 Aug 8. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023.

3. Hetzel B. Iodine deficiency disorders (IDD) and their eradication. Lancet. 1983;322(8359):1126-1129. doi: https://doi.org/10.1016/S0140-6736(83)90636-0

4. Zimmermann MB, Jooste PL, Pandav CS. Iodinedeficiency disorders. Lancet. 2008;372(9645):1251-1262. doi: https://doi.org/10.1016/S0140-6736(08)61005-3

5. Hintze G, Koebberling J. Treatment of iodine deficiency goiter with iodine, levothyroxine or a combination of both. Thyroidology. 1992;(4):37-40.

6. Gartner R, Dugrillon A, Bechtner G. Evidence that iodolactones are the mediators of growth inhibition by iodine on the thyroid. Acta Med Austriaca. 1996;23(1-2):47-51.

7. Rossijskaja associacija jendokrinologov. Rossijskaja associacija vrachej ul’trazvukovoj diagnostiki. Zabolevanija i sostojanija, svjazannye s deficitom joda. Klinicheskie rekomendacii. 2020. (In Russ.). Доступно по: https://rae-org.ru/system/files/documents/pdf/zabolevaniya_i_sostoyaniya_svyazannye_s_deficitom_yoda.pdf Ссылка активна на 15.07.2023.

8. Carlé A, Krejbjerg A, Laurberg P. Epidemiology of nodular goitre. Influence of iodine intake. Best Pract Res Clin Endocrinol Metab. 2014;28(4):465-479. doi: https://doi.org/10.1016/j.beem.2014.01.001

9. Unlu MT, Kostek M, Aygun N, et al. Non-Toxic Multinodular Goiter: From Etiopathogenesis to Treatment. Sisli Etfal Hastan Tip Bul. 2022;56(1):21-40. doi: https://doi.org/10.14744/SEMB.2022.56514

10. Troshina EA, Platonova NM, Panfilova EA, Panfilov KO. The analytical review of monitoring of the basic epidemiological characteristics of iodine deficiency disorders among the population of the Russian Federation for the period 2009—2015. Problems of Endocrinology. 2018;64(1):21-37. doi: https://doi.org/10.14341/probl9308

11. Magomedov AG, Dibirov AD, Abdulkhalikov AS, et al. Giant goiter in the practice of endocrine surgery (description series of observations). Vestnik DGMA. 2014;3(12):66-68. (In Russ.).

12. Anders HJ. Compression syndromes caused by substernal goitres. Postgrad Med J. 1998;74(872):327-329. doi: https://doi.org/10.1136/pgmj.74.872.327

13. Din WBM, Farrar E, Liu C, Moor J. Cough syncope and tracheal compression secondary to a retrosternal goitre: looking for a pulmonary embolism. BMJ Case Rep. 2019;12(4):e228997. doi: https://doi.org/10.1136/bcr-2018-228997

14. Abdullah AS, Bahjat AS, Mohammed AA. Huge toxic goiter extending to the posterior mediastinum; Case report with literature review. Int J Surg Case Rep. 2019;62(1):69-72. doi: https://doi.org/10.1016/j.ijscr.2019.08.016

15. Anders HJ. Compression syndromes caused by substernal goitres. Postgrad Med J. 1998;74(872):327-329. doi: https://doi.org/10.1136/pgmj.74.872.327

16. Hamdan A-L, Jabbour J, Al Zaghal Z, Azar ST. Goiter and Laryngopharyngeal Reflux. ISRN Endocrinol. 2012;2012(1):1-6. doi: https://doi.org/10.5402/2012/208958

17. Agger-Nielsen H, Døssing H, Sørensen JR. Syncope due to giant goitre. Ugeskr Laeger. 2018;180(24):V01180048

18. Hauten P, Bleumink G, Hovens M, et al. Unexpected Complication of a Multinodular Goitre. Eur J Case Reports Intern Med. 2016;3(2):190-195. doi: https://doi.org/10.12890/2016_000363

19. McNeill CJ, Sinnott JD, Howlett D. Bilateral brachiocephalic vein compression: an unusual and rare presentation of multinodular goitre. BMJ Case Rep. 2016;3(2):bcr2016217074. doi: https://doi.org/10.1136/bcr-2016-217074

20. Manning PB, Thompson NW. Bilateral phrenic nerve palsy associated with benign thyroid goiter. Acta Chir Scand. 1989;(155):429-430

21. Bellantone R, Lombardi CP, Bossola M, et al. Total thyroidectomy for management of benign thyroid disease: Review of 526 cases. World J Surg. 2002;26(12):1468-1471. doi: https://doi.org/10.1007/s00268-002-6426-1

22. Vetshev PS, Yankin PL, Zhivotov VA, et al. Risk factors and prognosis of voice disorders after surgical treatment of thyroid and parathyroid diseases. Pirogov Russian Journal of Surgery. 2019;(4):5-14. doi: https://doi.org/10.17116/hirurgia20190415

23. Belokonev VI, Pushkin SYu, Kovaleva ZV, et al. Safe thyroidectomy for thyroid and parathyroid diseases. Pirogov Russian Journal of Surgery. 2022;(6):62-71. doi: https://doi.org/10.17116/hirurgia202206162

24. Shulutko AM, Semikov VI, Gryaznov SE, et al. Risk of hypocalcemia after thyroid surgery. Pirogov Russian Journal of Surgery. 2015;(11):35-40. doi: https://doi.org/10.17116/hirurgia20151135-40


Supplementary files

1. Fig. 1. The patient's neck area
Subject
Type Исследовательские инструменты
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2. Fig. 2. CT scan
Subject
Type Исследовательские инструменты
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Indexing metadata ▾

Review

For citations:


Demidova T.Yu., Kochina A.S., Ibrokhimov Kh.Kh., Khalilaeva A.P. Compression syndrome in giant euthyroid goiter. Clinical and experimental thyroidology. 2022;18(4):14-19. (In Russ.) https://doi.org/10.14341/ket12752

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