Possible Consequences of Changing of the TSH Reference Ranges
https://doi.org/10.14341/ket20095230-33
Abstract
We retrospectively analyzed the results of measurements of serum TSH and free T4 concentrations performed in1014 patients hospitalised in Federal Endocrinological Research Center without known thyroid disorders. According to the present TSH reference ranges (0.4–4.0 mU/l), prevalence of a hypothyroidism in the sample was10% (n = 104). For an estimation of possible consequences of lowering TSH reference interval prevalence of TSH> 2.5 mU/l has been calculated as 24% (n = 250). Тhus, in case of reduction of upper limits for TSH the quantity of persons with a hypothyroidism can increase in 2,5 times.
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, , , Possible Consequences of Changing of the TSH Reference Ranges. Clinical and experimental thyroidology. 2009;5(2):30-33. (In Russ.) https://doi.org/10.14341/ket20095230-33
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