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Clinical and experimental thyroidology

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Features of carbohydrate metabolism in a patient with type 1 diabetes mellitus in subclinical hypothyroidism in the outcome of chronic autoimmune thyroiditis

https://doi.org/10.14341/ket9748

Abstract

Diabetes mellitus and primary hypothyroidism, in the outcome of chronic autoimmune thyroiditis, the two most common diseases in endocrinology and the practicing doctor are important not to forget about the possible association of these pathologies. This applies to patients with diabetes mellitus, both 1 and 2 types. However, the combination of these two pathologies is more common in type 1 diabetes, which is due to the autoimmune nature of these diseases. A clinical case of a patient with type 1 diabetes mellitus, which is on pump insulin therapy, is presented, which, in the background of previously selected therapy, during the last 2 months, episodes of hypoglycemia increased. In the course of the survey, primary subclinical hypothyroidism was identified, in the outcome of chronic autoimmune thyroiditis. Against the background of the achievement of euthyroidism, it was possible to achieve compensation of carbohydrate metabolism without correction of previously selected insulin therapy. The high incidence of thyroid dysfunction in patients with diabetes mellitus, and as a consequence, the deterioration in the compensation of carbohydrate metabolism, requires a systematic screening of thyroid disorders in the presence of diabetes mellitus.

About the Authors

Margarita S. Mikhina

Endocrinology Research Centre


Russian Federation

research associate



Ekaterina A. Troshina

Endocrinology Research Centre


Russian Federation

MD, PhD, Professor



Tatiana V. Nikonova

Endocrinology Research Centre


Russian Federation

MD, PhD, Professor



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Supplementary files

1. Fig. 1. Continuous monitoring of glucose levels before the treatment of subclinical hypothyroidism of May 11–15, 2018 (Freestyle Libre, Abbott, USA)
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2. Fig. 2. Continuous monitoring of glucose levels during the treatment of subclinical hypothyroidism 05.30–01.06.2018 (iPro 2, Medtronic MiniMed, USA)
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Type Исследовательские инструменты
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Review

For citations:


Mikhina M.S., Troshina E.A., Nikonova T.V. Features of carbohydrate metabolism in a patient with type 1 diabetes mellitus in subclinical hypothyroidism in the outcome of chronic autoimmune thyroiditis. Clinical and experimental thyroidology. 2018;14(4):206-209. (In Russ.) https://doi.org/10.14341/ket9748

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ISSN 1995-5472 (Print)
ISSN 2310-3787 (Online)